SUMMARYThe flexibility of the Multi-Link (ML) PENTA stent with platform 0.09 to 0.12-mmthick struts and 12% to 16% metal/artery coverage was improved to facilitate safe delivery in complex coronary lesions. The present study was designed to evaluate the clinical (9-month) and angiographic (6-month) results of the ML PENTA stent in complex coronary lesions (modified American College of Cardiology/American Heart Association lesion type B2 or C) and to determine independent factors correlated with target lesion revascularization. The study population consisted of 86 consecutive patients who had undergone successful coronary ML PENTA stent implantation for coronary artery disease from May 2003 to July 2004 in our hospital. During the follow-up period, cardiac events were documented in 21 (24.4%) of the 86 patients. Target lesion revascularization was required in 16 (18.6%) of the 86 patients. Single logistic regression analysis showed that target lesion revascularization was significantly correlated with lesion length > 2.0 cm, residual percent diameter stenosis after the procedure > 20%, and multiple stents. Multiple logistic regression analysis showed that residual percent diameter stenosis after procedure > 20% (P = 0.0125, odds ratio = 11.585) was the significant explanatory factor of target lesion revascularization. The results of the present study suggest that 9-month clinical and 6-month angiographic outcomes in patients with coronary artery disease treated using the ML PENTA stent were excellent and target lesion revascularization after coronary ML PENTA stent implantation was influenced by residual percent diameter stenosis after the procedure. (Int Heart J 2005; 46: 997-1006) Key words: Multi-Link PENTA stent, Target lesion revascularization, Residual percent diameter stenosis THE flexibility of the Multi-Link (ML) PENTA stent (Guidant, Santa Clara, California) with platform 0.09 to 0.12-mm-thick struts and 12% to 16% metal/ artery coverage, which is a recently developed stent, has been improved to facilitate safe delivery in complex coronary lesions and the stent maintains sidebranch access with the possibility to expand the cell toward the side branch up to From the