The in vitro effect of Garden Thyme (Thymus vulgaris L.) extract on Brachyspira hyodysenteriae

Abstract

Filtrates of a water extract of commercially available garden thyme (Thymus vulgaris L.) were used for studying its possible bactericidal effect on Brachyspira hyodysenteriae, the causative agent of swine dysentery, by agar-diffusion technique. Five of the six studied Brachyspira strains have proven to be sensitive and one moderately sensitive in the in vitro tests. It was concluded that water extract of garden thyme possesses inhibitory effects against B. hyodysenteriae. In vivo experiments are needed to check the validity of this conclusion.

The Efficacy of Two Phytogenic Feed Additives in the Control of Swine Dysentery

“…Besides, herbal-based products are generally recognized as safe (GRAS), and do not cause resistance in bacteria or adverse effects on animal health and consumer safety [21,26]. However, only in a few in vitro studies, the activity of herbal-derived compounds against B. hyodysenteriae was tested [29][30][31]. In our study, the effi cacy of phytogenic products in the prevention and control of outbreaks of SD was monitored in vivo, by evaluating the effects of two phytogenic feed additives, Patente-Herba® and Patente-Herba® Plus.…”

“…Besides, feed supplemented with coated trans-cinnamaldehyde reduced Brachyspira colonization in in vivo experiments with young pullets [28]. Recently, the effi cacy of herbal components against B. hyodysenteriae was tested in several separate studies [29][30][31], but they were all conducted in vitro. However, in order to verify the effi ciency of the extract, all the above mentioned authors made a note that its effects should be tested in fi eld conditions.…”