The Incidence and Risk Factors for Lower Limb Skin Graft Failure

Reddy, S. V. R.; El‐Haddawi, Falah; Fancourt, Michael; Farrant, Glenn; Gilkison, William; Henderson, Nigel; Kyle, Stephen; Mosquera, Damien

doi:10.1155/2014/582080

Cited by 48 publications

(43 citation statements)

References 12 publications

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“…48 However, infection is a significant problem that can cause graft failure and prevention or treatment of infection is a requirement for optimizing graft take. 49 The use of DACC-coated hydrogel dressings for fixation of grafts after surgery was assessed in a 7-patient evaluation. 50 After treatment with the DACC-coated dressing and a tie-over dressing (fine cotton gauze to help secure primary dressing in position), the wounds were assessed for infection at 5, 14-and 30-days post-surgery.…”

Section: Skin Graftingmentioning

confidence: 99%

Bacterial-binding dressings in the management of wound healing and infection prevention: a narrative review

Chadwick

Ousey

2019

J Wound Care

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The aim of this review was to present the clinical data on the use of the family of bacterial-binding dressings (Sorbact; dialkylcarbamoyl chloride-coated) in the treatment of a variety of acute and chronic wounds. The findings are discussed in terms of the effectiveness of the bacterial-binding dressings on bacterial bioburden reduction, infection prevention, initiation/progression of wound healing and cost-effectiveness. The evidence in support of the bacterial-binding dressings is strongest in the area of infection prevention in surgical wounds, with several controlled trials showing the prophylactic benefit of the dressing in these wounds. Wound bioburden management in chronic wounds is supported by a number of clinical studies. In total, 29 published clinical studies (with a total of 4044 patients) were included in this review.

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Section: Skin Graftingmentioning

confidence: 99%

Bacterial-binding dressings in the management of wound healing and infection prevention: a narrative review

Chadwick

Ousey

2019

J Wound Care

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“…Second hemostasis is readily and rapidly achieved with the use of a topical gelatin-thrombin matrix following excision of the nasal septal mucosa. A dry surgical field is imperative when placing the STSG as this diminishes the likelihood of graft hematoma and subsequent failure of the graft [ 26 – 28 ]. Finally, by using a fibrin tissue glue, nasal packing is not required to secure the graft, arrest bleeding, nor to prevent post-operative hematoma.…”

Section: Discussionmentioning

confidence: 99%

Technique modifications for septodermoplasty: An illustrative case

Bastianelli

Kilty

2015

Journal of Otolaryngology - Head & Neck Surgery

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BackgroundHereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease that results in telangiectasia of the sinonasal tract, gastro-intestinal tract as well as possible arteriovenous malformations of the lung, liver and brain. One of the most common disease manifestations of HHT is epistaxis. Severe recurrent epistaxis necessitating iron therapy and blood transfusion is often managed with septodermoplasty. Its initial description was as an open surgical technique requiring nasal packing.Case presentationWe describe a modified approach to septodermoplasty done completely endoscopically and without nasal packing for a patient with severe epistaxis due to HHT.ConclusionThe described technique modifications for the presented case allowed for same day discharge following surgery, complete take of the skin graft and resultant epistaxis control that ended thepatient's transfusion dependency. The merits of these modifications should be further evaluated in a clinical trial.

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“…Skin graft 'take' however is also affected by the wound location (lower extremities had higher failure rates), high body mass index, immunosuppressant drug use, and peripheral blood vessel disease. [11,12] Therefore this experiment aims to analyze the effectiveness of autologous PRP in comparison with conventional suture fixation in skin graft transfer for deep burn patients. We conducted an intra-patient study to avoid differing risk factors between the test subjects.…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Autologous Platelet-Rich Plasma vs Conventional Mechanical Suture Fixation in Skin Graft Transfer for Deep Burn Patients: An Intra-Patient Controlled Study

Hasibuan¹,

Hudaya²

2019

AJCMR

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Background: Autologous platelet-rich plasma (PRP) is a patient-derived treatment containing fibrin and high concentrations of growth factors, often known for its adhesive and hemostatic abilities. PRP has been used for various types of wounds, including chronic and burn wounds. Autologous PRP is an affordable and practical modality that has been advocated by multiple publications due to its effect in improving clinical outcomes and wound healing time in regard to skin graft in burn patients. The aim of this study is to compare the effectiveness of PRP to conventional suture fixation in skin graft transfer for deep burn patients through objective "take" percentage analysis. Methods: This controlled prospective single center study included 15 deep burn patients with a total burn area of 5-30% on their extremities. Each patient received skin graft treatments using both methods: autologous PRP and conventional sutures. Pictures and analysis were taken on the third day after surgery to compare the open wound area between the two methods. Result: There was no significant "take" percentage difference between the autologous PRP and conventional suture group. The mean percentage of skin graft "take" for autologous PRP was 84.36% ± 13.82%, and the result for suture fixation was 84.16% ± 15.33%. Conclusion: The use of autologous PRP in this study did not improve the "take" percentage of skin grafts compared to conventional suture fixation. However, the use of autologous PRP did reduce the surgery duration and is still a treatment modality with high potential.

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The Incidence and Risk Factors for Lower Limb Skin Graft Failure

Cited by 48 publications

References 12 publications

Bacterial-binding dressings in the management of wound healing and infection prevention: a narrative review

Bacterial-binding dressings in the management of wound healing and infection prevention: a narrative review

Technique modifications for septodermoplasty: An illustrative case

The Effectiveness of Autologous Platelet-Rich Plasma vs Conventional Mechanical Suture Fixation in Skin Graft Transfer for Deep Burn Patients: An Intra-Patient Controlled Study

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