The incidence of biopsy‐proven glomerulonephritis in Australia

Briganti, Esther M.; Dowling, John P.; Finlay, Moira; Hill, Prue; Jones, Colin L.; Kincaid‐Smith, Priscilla; Sinclair, R.; McNeil, John J; Atkins, Robert C.

doi:10.1093/ndt/16.7.1364

Cited by 188 publications

(188 citation statements)

References 8 publications

Supporting

Mentioning

156

Contrasting

Unclassified

Order By: Relevance

“…The incidence of MPGN has been reported to decrease over time from about 7-10% in the 1970s to about 2% during 1990-2011 [3][4][5][6][16][17][18][19]. In the present study, among the 26,535 patients with biopsy-confirmed disease, 593 (2.2%) patients were registered as having a histopathology of MPGN types I and III.…”

Section: Discussionmentioning

confidence: 44%

“…Further, 332 out of the 26,535 (1.3%) patients were registered as primary MPGN. In a comprehensive epidemiological study, the lesion of MPGN was observed in about 2% of patients with biopsy-confirmed glomerulonephritis in the Australia [3] and United States [19]. As for primary MPGN, a recent report from Japan has showed a 1.2% incidence of primary MPGN in a total of 6,369 renal biopsies [17].…”

Section: Discussionmentioning

confidence: 99%

“…In the clinical setting, MPGN is one of the most common causes of nephrotic syndrome in both children and adults, and accounts for approximately 2-10% of all cases of biopsy-confirmed glomerulonephritis [3][4][5][6]. Traditionally, MPGN has been classified based on the findings of electron microscopy as primary MPGN type I (MPGN I), MPGN II, MPGN III, or secondary MPGN [1,2].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical features and pathogenesis of membranoproliferative glomerulonephritis: a nationwide analysis of the Japan renal biopsy registry from 2007 to 2015

et al. 2017

View full text Add to dashboard Cite

Background The incidence and age distribution of membranoproliferative glomerulonephritis (MPGN) vary throughout the world by race and ethnicity. We sought to evaluate the clinical features, pathogenesis, and age distribution of MPGN among a large nationwide data from the Japan Renal Biopsy Registry (J-RBR). Methods A cross-sectional survey of 593 patients with MPGN (types I and III) registered in the J-RBR between 2007 and 2015 was conducted. Clinical parameters, and laboratory findings at diagnosis were compared between children (< 20 years), adults (20-64 years), and elderly patients (≥ 65 years). Results The median age of the patients was 59.0 years and mean proteinuria was 3.7 g/day. The rate of nephrotic syndrome was significantly higher in adults (40.4%) and elderly patients (54.0%) than in children (14.9%), whereas the rate of chronic glomerulonephritis was significantly higher in children (66.2%) than in adults (34.4%) and elderly patients (31.2%). According to the CGA risk classification, high-risk (red zone) cases accounted for 3.4% of children, 52.5% of adults and 84.1% of elderly patients with MPGN. As for pathogenesis, primary MPGN was most frequent (56.0%). Lupus nephritis was the most common disease among adult patients with secondary MPGN, whereas infectious disease was more common in elderly patients. Multiple regression analysis revealed that high systolic blood pressure and high proteinuria were independent factors associated with decreased estimated glomerular filtration rate (eGFR) in adults and elderly patients with MPGN. Conclusions In Japan, adults and elderly patients with MPGN had a lower eGFR and severer proteinuria than children.

show abstract

Section: Discussionmentioning

confidence: 44%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical features and pathogenesis of membranoproliferative glomerulonephritis: a nationwide analysis of the Japan renal biopsy registry from 2007 to 2015

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Since 128,057,352 people resided in Japan in 2010, the estimated rate of renal biopsy was 140.6 to 164.0 per million population. This rate was higher than that in Romania [24], Spain [25], the Czech Republic [10], Denmark [26], and Scotland [27], was similar to that in France [28], and was lower than that in USA, Finland [29], and Australia [30].…”

Section: Discussion and Commentsmentioning

confidence: 62%

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010

et al. 2013

View full text Add to dashboard Cite

123Clin Exp Nephrol (2013) 17:155-173 DOI 10.1007 nephritic syndrome (55.4 % and 50.0 % in 2009 and 2010, respectively), followed by nephrotic syndrome (22.4 % and 27.0 %); the most frequent pathological diagnosis as classified by the pathogenesis was IgA nephropathy (31.6 % and 30.4 %), followed by primary glomerular diseases (except IgA nephropathy) (27.2 % and 28.1 %). Among the primary glomerular diseases (except IgA nephropathy) in the patients with nephrotic syndrome, membranous nephropathy was the most common histopathology in 2009 (40.3 %) and minor glomerular abnormalities (50.0 %) were the most common in 2010 in native kidneys in the J-RBR. Five new secondary and longitudinal research studies by the J-KDR were started in 2009 and one was started in 2010.

show abstract

“…IgA nephropathy is the most common primary glomerulopathy among all races from Europe [3][4][5], Asia [6,7], and Australia [8] with the exception of the black race [9]. Nair et al demonstrated that IgA nephropathy patients increase as the primary glomerulopathy among young adults (20-39 years old) in the USA [10].…”

Section: Introductionmentioning

confidence: 99%

Enhanced intrarenal oxidative stress and angiotensinogen in IgA nephropathy patients

Kobori

Katsurada

Ozawa

et al. 2007

Biochemical and Biophysical Research Communications

View full text Add to dashboard Cite

This study was performed to determine whether immunoreactivity of intrarenal hemeoxygenase-1 and angiotensinogen are increased in IgA nephropathy (IgAN) patients. Hemeoxygenase-1 and angiotensinogen immunoreactivity were determined by immunohistochemistry robot system in renal specimens from 39 patients with IgAN. Normal portions of surgically resected kidney served as controls. IgAN patients showed moderate proteinuria (1.1+/−0.2 g/day); however, the control group did not show any proteinuria. Immunoreactivity of intrarenal hemeoxygenase-1 and angiotensinogen in IgAN were significantly increased compared to normal kidneys (2.42+/−0.42 vs 1.00+/−0.26 for hemeoxygenase-1 and 4.05+/−0.40 vs 1.00+/−0.21 for angiotensinogen, arbitrary unit). Even though these IgAN patients did not show massive renal damage, hemeoxygenase-1 and angiotensinogen immunoreactivity were increased in these patients at this time point. These data suggest that activated intrarenal reactive oxygen species-angiotensinogen axis plays some roles in development of IgAN at the early stage and will provide supportive foundation of effectiveness of the renin-angiotensin system blockade in IgAN.

show abstract

The incidence of biopsy‐proven glomerulonephritis in Australia

Abstract: This review has provided population-based descriptive epidemiological data on clinically significant glomerulonephritis. This data provides important clues for further studies relating to the identification of risk factors for the various types of glomerulonephritis.

Cited by 188 publications

References 8 publications

Clinical features and pathogenesis of membranoproliferative glomerulonephritis: a nationwide analysis of the Japan renal biopsy registry from 2007 to 2015

Clinical features and pathogenesis of membranoproliferative glomerulonephritis: a nationwide analysis of the Japan renal biopsy registry from 2007 to 2015

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010

Enhanced intrarenal oxidative stress and angiotensinogen in IgA nephropathy patients

Contact Info

Product

Resources

About