The Incidence of Fibromyalgia and Its Associated Comorbidities

Weir, Peter; Harlan, Gregory A.; Nkoy, Flo L.; Jones, Spencer S.; Hegmann, Kurt T.; Gren, Lisa H.; Lyon, Joseph L.

doi:10.1097/01.rhu.0000221817.46231.18

Cited by 275 publications

(60 citation statements)

References 19 publications

(23 reference statements)

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“…1988), while fibromyalgia, epilepsy, and IHD are associated with increased prevalence of both depression and anxiety disorders (Weir et al. 2006; Tellez‐Zenteno et al. 2007; Janssens et al.…”

Section: Discussionmentioning

confidence: 99%

Physical comorbidities increase the risk of psychiatric comorbidity in multiple sclerosis

et al. 2016

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BackgroundRisk factors for psychiatric comorbidity in multiple sclerosis (MS) are poorly understood.ObjectiveWe evaluated the association between physical comorbidity and incident depression, anxiety disorder, and bipolar disorder in a MS population relative to a matched general population cohort.MethodsUsing population‐based administrative data from Alberta, Canada we identified 9624 persons with MS, and 41,194 matches. Using validated case definitions, we estimated the incidence of depression, anxiety disorder, and bipolar disorder, and their association with physical comorbidities using Cox regression, adjusting for age, sex, socioeconomic status, and index year.ResultsIn both populations, men had a lower risk of depression and anxiety disorders than women, as did individuals who were ≥45 years versus <45 years at the index date. The risk of bipolar disorder declined with increasing age. The risks of incident depression (HR 1.92; 1.82–2.04), anxiety disorders (HR 1.52; 1.42–1.63), and bipolar disorder (HR 2.67; 2.29–3.11) were higher in the MS population than the matched population. These associations persisted essentially unchanged after adjustment for covariates including physical comorbidities. Multiple physical comorbidities were associated with psychiatric disorders in both populations.ConclusionPersons with MS are at increased risk of psychiatric comorbidity generally, and some physical comorbidities are associated with additional risk.

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Section: Discussionmentioning

confidence: 99%

Physical comorbidities increase the risk of psychiatric comorbidity in multiple sclerosis

et al. 2016

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“…Relative risk ratios (RR) between FM and OA and FM and control samples were calculated based on the proportion in each sample with comorbid conditions. 2 tests were used to compare between-sample differences for dichotomous or categorical variables, and t tests were used to compare continuous variables with minimal skewness in the distribution. Differences in continuous measures of utilization and costs were compared using nonparametric Wilcoxon ranksum tests.…”

Section: Methodsmentioning

confidence: 99%

Employees With Fibromyalgia: Medical Comorbidity, Healthcare Costs, and Work Loss

White

Birnbaum

Kaltenboeck

et al. 2008

Journal of Occupational &Amp; Environmental Medicine

153

185

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• Compare prevalence rates of common comorbid conditions in employees diagnosed as having fibromyalgia (FM) or osteoarthritis (OA).• Identify trends in the use of medical care and prescription drugs by employees having FM or OA, as compared to control subjects.• Contrast total dollar costs and their components-medical costs, drug costs, and indirect costs of time lost from work-in employees with FM, those with OA, and control employees having neither of these disorders. ($10,199) approached OA costs ($10,861, P ϭ 0.3758) Med. 2008;50:13-24)

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“…3 The majority of studies on FM acknowledge the gender differences within the prevalence rates, such that women are 7 to 10 times more likely than men to be diagnosed with FM. [8][9][10] The symptoms of FM often overlap with other conditions thought to be "psychosomatic," such as chronic fatigue syndrome, 11 chronic headache, [12][13][14] irritable bowel syndrome, [15][16][17] and temporomandibular joint disorder. 18,19 Many studies have found strong associations with psychosocial distress, specifically depression, in FM populations.…”

mentioning

confidence: 99%

Fibromyalgia Syndrome in Chronic Disabling Occupational Musculoskeletal Disorders

Howard

Mayer

Neblett

et al. 2010

Journal of Occupational &Amp; Environmental Medicine

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The Incidence of Fibromyalgia and Its Associated Comorbidities

Abstract: Females are more likely to be diagnosed with fibromyalgia than males, although to a substantially smaller degree than previously reported, and there are strong associations for comorbid conditions that are commonly thought to be associated with fibromyalgia.

Cited by 275 publications

References 19 publications

Physical comorbidities increase the risk of psychiatric comorbidity in multiple sclerosis

Physical comorbidities increase the risk of psychiatric comorbidity in multiple sclerosis

Employees With Fibromyalgia: Medical Comorbidity, Healthcare Costs, and Work Loss

Fibromyalgia Syndrome in Chronic Disabling Occupational Musculoskeletal Disorders

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