The indirect impact of the COVID-19 pandemic on people with type 2 diabetes mellitus and without COVID-19 infection: Systematic review and meta-analysis

Hu, Zhuoran; Youn, Hin Moi; Quan, Jianchao; Lee, Lily Luk Siu; Mak, Ivy Lynn; Yu, Esther Yee Tak; Chao, David Vai-Kiong; Ko, Welchie W. K.; Wong, Ian C. K.; Lau, Gary K. K.; Lau, Yu Lung; Lam, Cindy L. K.; Wan, Eric Yuk Fai

doi:10.1016/j.pcd.2023.02.006

Cited by 4 publications

(2 citation statements)

References 59 publications

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“…There are a number of studies that evaluated the impact of COVID-19 pandemic on the outcomes of patients with T2D [28]; however, the findings were inconsistent. Some of our findings were in line with previous studies, and some were in contrast.…”

Section: Discussionmentioning

confidence: 99%

Impact of the COVID-19 pandemic on the outcomes of Indonesian chronic disease management program

Salamah,

Ramadhani,

Arfiana

et al. 2023

ELECTRON J GEN MED

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Background: The Indonesian Government launched chronic disease management program (PROLANIS) with the aim of improving clinical outcomes and preventing disease complications of patients with type 2 diabetes (T2D). During the coronavirus disease 2019 (COVID-19) pandemic, the overwhelmed healthcare system shifted resources away from non-communicable diseases in the attempt to mitigate it. Thus, the implementation of PROLANIS during the COVID-19 pandemic might not be as optimal as before the pandemic era, leading to worse clinical outcomes. This pilot study aims to evaluate the impact of the COVID-19 pandemic on PROLANIS in rural areas by analyzing the changes of metabolic control and renal function parameters. Methods: This study used data from three PROLANIS groups report in rural areas in East Java Province, Indonesia. Study population was PROLANIS participants who came for six-month-evaluation in December 2019 (T0), June 2020 (T1), and December 2020 (T2). Evaluated metabolic control parameters were body mass index (BMI), blood pressure, hemoglobin A1C (HbA1C), total cholesterol (TC), high-density lipid, low-density lipid, and triglyceride (TG), whereas evaluated renal function parameters were blood urea nitrogen, serum creatinine, and urinary albumin. Independent t-test and Wilcoxon signed-rank test were used for statistical analyses. p-value <0.05 was considered statistically significant. Results: Among 52 PROLANIS participants included in the analyses, four metabolic control parameters (BMI, blood pressure, TC, and TG) and all renal function parameters significantly worsened right after the pandemic started but improved 6 months afterwards. Meanwhile, HbA1C continuously worsened throughout the study period, albeit statistically insignificant. Conclusions: The metabolic control and renal function parameters in our study population deteriorates especially in the beginning of the COVID-19 pandemic.

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Section: Discussionmentioning

confidence: 99%

Impact of the COVID-19 pandemic on the outcomes of Indonesian chronic disease management program

Salamah,

Ramadhani,

Arfiana

et al. 2023

ELECTRON J GEN MED

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“…A panoramic view across eleven observational studies unveils a landscape of stability. The meta-analysis casts its verdict, revealing no significant fluctuations in HbA1c levels [weighted mean difference (WMD), 0.06 [95% CI −0.12 to 0.24)] and body mass index (BMI) [0.15 (95% CI −0.24 to 0.53)] between the pre-pandemic and pandemic epochs (8) . In a counterpoint, a Spanish study illuminates an intriguing facet.…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Glycosylated Haemoglobin and Dyslipidaemia in Individuals Exposed to COVID-19: A Cross Sectional Study in North Indian Population

Kumar,

Vijayasimha,

Sarkar

et al. 2023

IJST

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Objective: To investigate the correlation between Glycosylated Hemoglobin and dyslipidemia in individuals exposed to COVID-19 in the Delhi/NCR region. Method: In the Delhi/NCR region, a total of 521 patient fasting blood samples were gathered from a NABL Accredited labs. These samples, collected between July 2020 and March 2022, consisted of 334 males and 187 females. HbA1C and lipid profile tests for the patients were conducted using conventional methods at a laboratory located in Gurugram. Findings: Among diabetic patients below 40 years of age, the mean HDL levels decreased to 40.3% compared to 42 mg/dl in non-diabetics. Increased glycosylated hemoglobin [more than 7%] with dyslipidemia noted in males 114 compared to females 64. A significant decrease in HDL levels were observed in diabetic patients above 40 years of age, with the mean level of HDL dropping to 33 mg/dl. The dyslipidemia was present in 80.9% of male diabetic patients and 88.6% of female diabetic patients. In diabetic male patients, a correlation between increasing triglyceride levels and the decreased HDL levels found. The mean triglyceride level in diabetic patients was 199 mg/dl, while the mean HDL level was 42 mg/dl. On the other hand, non-diabetic individuals had a mean triglyceride level of 105 mg/dl and an HDL level of 44 mg/dl. Novelty: Dyslipidemia is significantly associated with poorly controlled HbAa1c in T2DM than non-diabetic subjects after covid exposure. This observation points towards a U-shaped correlation between HDL and glycated haemoglobin in diabetic patients.

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Influence of the COVID-19 pandemic on the achievement of guideline targets for HbA1c, blood pressure, and LDL cholesterol in people with diabetes in Japan

Kuwajima,

Itoh,

Sato

et al. 2024

Diabetol Int

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The indirect impact of the COVID-19 pandemic on people with type 2 diabetes mellitus and without COVID-19 infection: Systematic review and meta-analysis

Cited by 4 publications

References 59 publications

Impact of the COVID-19 pandemic on the outcomes of Indonesian chronic disease management program

Impact of the COVID-19 pandemic on the outcomes of Indonesian chronic disease management program

Relationship Between Glycosylated Haemoglobin and Dyslipidaemia in Individuals Exposed to COVID-19: A Cross Sectional Study in North Indian Population

Influence of the COVID-19 pandemic on the achievement of guideline targets for HbA1c, blood pressure, and LDL cholesterol in people with diabetes in Japan

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