The influence of a biopsychosocial-based treatment approach to primary overt hypothyroidism: a protocol for a pilot study

Brown, Benjamin T.; Bonello, Rod; Pollard, Henry

doi:10.1186/1745-6215-11-106

Cited by 10 publications

(6 citation statements)

References 28 publications

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“…These impact current societal and future health of the nation in a manner no other non-communicable disease (NCD) does ( 1 ). Hypothyroidism, the most common cause of pathological hormone deficiency ( 2 ), results due to the insufficient functioning of the thyroid gland to produce thyroid hormone ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

Health information-seeking behavior among hypothyroid patients at Saveetha Medical College and Hospital

Perumal

Prasad²,

Surapaneni

et al. 2015

Ethiop J Health Sci

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BACKGROUND: Hypothyroidism causes considerable morbidity. Low knowledge coupled with inadequate health literacy may lead to poor prevention and management. This study aimed to assess health information-seeking behavior and hypothyroid knowledge among South Indian hypothyroid patients. METHODS: This cross-sectional study was conducted in October 2013 in Saveetha Medical College, Chennai, India. Hundred clinically diagnosed hypothyroid patients >18 years were interviewed in a hospital using a 57-item questionnaire to gather information on their socio-demographics, self-reported disease history, hypothyroid-related knowledge, health information sources, health literacy and health information-seeking behavior. Hypothyroidism was assessed by free T3 and T4 levels. RESULTS: Mean age of participants was 38 years (SD=12) with median age of 39.5 years, majority of the participants being females (77%) and living in urban setting (52%). Mean free T3 level was 0.0137ng/dl (SD= 0.003) and mean free T4 was 0.7ng/dl (SD= 0.06). Ninety three percent of the participants received initial hypothyroidism education from their physicians at the time of diagnosis. Half of the participants had incorrect hypothyroidism-related knowledge; similar between both genders. Participants with inadequate health literacy had poor knowledge about the hypothyroidism. Hypothyroidism-related health information was sought almost exclusively from health professionals, predominantly regarding treatment, linked to their faith in qualified medical assistance. Economic status primarily determined healthcare-seeking behavior. Marital status, education level, annual household income and health literacy were significantly associated with knowledge. CONCLUSION: Participants having higher educational qualification, higher annual household income and adequate health literacy had considerable knowledge about hypothyroidism. Developing multifactorial and tailored health education for patients with marginal or inadequate health literacy is needed. Exploring healthcare institutions as a medium for delivery of such education should be explored.

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Section: Introductionmentioning

confidence: 99%

Health information-seeking behavior among hypothyroid patients at Saveetha Medical College and Hospital

Perumal

Prasad²,

Surapaneni

et al. 2015

Ethiop J Health Sci

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“…Hypothyroidism is a prevalent endocrine condition. Individuals with this disease are commonly managed through supplementation with synthetic thyroid hormone, with the aim of alleviating symptoms and restoring normal thyroid-stimulating hormone levels [7] Levothyroxine, the treatment of choice, is inexpensive, easy to administer and in most cases restores well-being while normalizing thyroid function. However, 30-50% of individuals on levothyroxine are either over-treated or undertreated, and others remain dissatisfied with treatment despite achieving thyroid hormone concentrations within the laboratory reference interval [8].…”

Section: Discussionmentioning

confidence: 99%

Response of Hypothyroidism to Homeopathic Treatment: A Report of Three Cases

Dogra¹,

Mandal²

2020

Innovare J Med Sci

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Objectives:Hypothyroidism is a disease in which the thyroid gland does not produce enough thyroid hormone.It is the second most common endocrine disorder among women.Common causes are autoimmune disease such as Hashimoto’s thyroiditis, surgical removal of the thyroid and radiation therapy.Symptoms of Hypothyroidism include weight gain, alteration in cognition, fatigue, infertility and menstrual abnormalities.Thyroid stimulating hormone is highly sensitive to thyroid dysfunction and is used to evaluate thyroid disorders.Monotherapy with Levothyroxine is the standard for treating hypothyroidism in the conventional method.Apart from coventional method of treatment homoeopathy also has a scope in the treatment of hypothyroidism. Methods: This is a series of three cases which presented with symptoms of Hypothyroidism thoroughly evaluated and treated with constitutional homoeopathic medicine in a variable period of time.Assesment of thyroid stimulating hormone was done to see the improvement in the cases . Results: A marked improvement in the clinical symptoms as well as the pathological report was observed. Conclusion: This case series shows that Homoeopathic intervention can be used in the treatment of Hypothyroidism.

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“…A different therapeutic modality to be used in primary overt hypothyroidism called biopsychosocial approach, which was based on the use of a neuro-emotional-technique, was proposed in 2010 by Benjamin T. Brown [71] . They argued that this biopsychosocial model would be superior to the usual biomedical management of thyroid disease.…”

Section: How Effective Is Thyroxine Treatment? Also Known As Resolvinmentioning

confidence: 99%

Applying a systems approach to thyroid physiology: Looking at the whole with a mitochondrial perspective instead of judging single TSH values or why we should know more about mitochondria to understand metabolism

Moncayo¹,

Moncayo²

2017

BBA Clinical

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Classical thinking in endocrine physiology squeezes our diagnostic handling into a simple negative feedback mechanism with a controller and a controlled variable. In the case of the thyroid this is reduced to TSH and fT3 and fT4, respectively. The setting of this tight notion has no free space for any additions. In this paper we want to challenge this model of limited application by proposing a construct based on a systems approach departing from two basic considerations. In first place since the majority of cases of thyroid disease develop and appear during life it has to be considered as an acquired condition. In the second place, our experience with the reversibility of morphological changes makes the autoimmune theory inconsistent.While medical complexity can expand into the era of OMICS as well as into one where manipulations with the use of knock-outs and -ins are common in science, we have preferred to maintain a simple and practical approach. We will describe the interactions of iron, magnesium, zinc, selenium and coenzyme Q10 with the thyroid axis. The discourse will be then brought into the context of ovarian function, i.e. steroid hormone production. Finally the same elemental players will be presented in relation to the basic mitochondrial machinery that supports the endocrine.We propose that an intact mitochondrial function can guard the normal endocrine function of both the thyroid as well as of the ovarian axis. The basic elements required for this function appear to be magnesium and iron. In the case of the thyroid, magnesium-ATP acts in iodine uptake and the heme protein peroxidase in thyroid hormone synthesis. A similar biochemical process is found in steroid synthesis with cholesterol uptake being the initial energy-dependent step and later the heme protein ferredoxin 1 which is required for steroid synthesis. Magnesium plays a central role in determining the clinical picture associated with thyroid disease and is also involved in maintaining fertility. With the aid of 3D sonography patients needing selenium and/or coenzyme Q10 can be easily identified. By this we firmly believe that physicians should know more about basic biochemistry and the way it fits into mitochondrial function in order to understand metabolism. Contemplating only TSH is highly reductionistic.OutlineAuthor's profiles and motivation for this analysisThe philosophical alternatives in science and medicineReductionism vs. systems approach in clinical thyroid disease guidelinesThe entry into complexity: the involvement of the musculoskeletal systemIntegrating East and West: teachings from Chinese Medicine and from evidence based medicine (EBM)Can a mathematical model represent complexity in the daily thyroid practice?How effective is thyroxine treatment?Resolving the situation of residual symptoms in treated patients with thyroid diseaseImportance of iron, zinc and magnesium in relation to thyroid functionPutting together new concepts related to thyroid function for a systems approachExpanding our model into general aspects of ...

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The influence of a biopsychosocial-based treatment approach to primary overt hypothyroidism: a protocol for a pilot study

Cited by 10 publications

References 28 publications

Health information-seeking behavior among hypothyroid patients at Saveetha Medical College and Hospital

Health information-seeking behavior among hypothyroid patients at Saveetha Medical College and Hospital

Response of Hypothyroidism to Homeopathic Treatment: A Report of Three Cases

Applying a systems approach to thyroid physiology: Looking at the whole with a mitochondrial perspective instead of judging single TSH values or why we should know more about mitochondria to understand metabolism

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