The influence of age on blood pressure evaluation of hypertensive subjects

Lima, Nereida Kilza da Costa; Duarte, Paulo O.; Freiria, Mariana G. da; Almeida, E. F.; Rezende, Tatiana Maria Teodoro; Machado, Jaciara V.

doi:10.1016/j.archger.2009.07.004

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Elevated asleep systolic blood pressure (BP) and the lack of BP fall (dipping) have been associated with poorer cardiovascular outcome and are, amongst ABPM findings, the best prognostic markers of future cardiovascular events 13–16 . Studies have indicated that older patients have higher nighttime systolic BP as well as a reduced dipping and we hypothesize that these findings might be influenced by frailty 8,17 …”

Section: Introductionmentioning

confidence: 97%

The effect of frailty on the 24‐hour blood pressure pattern in the very elderly

Blauth

Vilar

Pontes

et al. 2021

J of Clinical Hypertension

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Frailty plays a crucial role in the management of hypertension in the very elderly and has a strong association with cardiovascular diseases. Nevertheless, its influence on the 24‐hour blood pressure pattern, including elevated asleep systolic blood pressure (BP) and the lack of BP fall during sleep (non‐dipping) has not been explored in a population above 80 years. Patients older than 80 years were classified into frail or robust subtypes by the five item frailty phenotype criteria. All participants were submitted to office blood pressure measurements and ambulatory BP monitoring over a 24‐hour period. Nocturnal dipping was defined as nighttime BP fall ≥10%. Thirty‐eight frail and 36 non‐frail individuals (mean age 85.3 ± 3.7 years; 67% females) were analyzed. Awake systolic and diastolic BP were similar for frail and robust individuals. Frail patients had higher systolic BP during sleep (128 ± 15 mm Hg vs. 122 ±13 mm Hg p = .04) and reduced systolic BP fall [1 (‐4.5 – 5)% vs. 6.8 (2.1 – 12.8)% p < .01]. Frailty was independently associated with higher risk of non‐dipping (OR 12.4; CI 1.79 – 85.9) and reduced nighttime systolic BP fall (‐6.1%; CI ‐9.6 – ‐2.6%). In conclusions, frailty has a substantial influence on nighttime BP values and pattern in patients older than 80 years.

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Section: Introductionmentioning

confidence: 97%