The influence of electromagnetic fields of industrial frequency on the male reproductive system
Abstract: Introduction. The safety of exposure to the population of a growing number of sources of electromagnetic fields everywhere, both in work and at home, has become a public health problem. This article presents the results of research on the study of the potentially adverse effects of electromagnetic fields of industrial frequency on the reproductive system of personnel of energy supply institutions. The aim of the study is to explore the possible adverse effects of electromagnetic fields of industrial frequency … Show more
Search citation statements
Paper Sections
Citation Types
Year Published
Publication Types
Relationship
Authors
Journals
Cited by 2 publications
References 14 publications
Markers of adipokine metabolism and hormonal-metabolic disorders in workers exposed to electric and magnetic fields of industrial frequency
Introduction. With the growth of urbanization processes, the problem of professional exposure to electric and magnetic fields of industrial frequency is an increasingly relevant topic. Recently, the scientists paid a special attention to the long-term health consequences associated with prolonged exposure to harmful physical factors. The previously obtained data on the increase in the levels of lipid metabolism and hormonal and metabolic disorders in workers exposed to electric and magnetic fields of industrial frequency determine the relevance of studying adipokine metabolism and assessing genetic risk factors for predisposition to cardiovascular pathology in employees of the electric power industry. The study aims to research the relationship of biochemical and molecular genetic markers of adipokine metabolism with indicators of hormonal and metabolic disorders for a comprehensive assessment of cardiovascular risk in workers exposed to electric and magnetic fields of industrial frequency. Materials and methods. The researchers examined 144 employees of the main group engaged in the repair and operation of power grid facilities and 40 employees of the control group who are not exposed to electromagnetic fields of industrial frequency.The concentration of leptin and adiponectin was determined in blood serum samples. The authors have calculated the ratio of adiponectin to leptin. We have performed a molecular genetic study of single nucleotide polymorphisms of leptin (LEP) G2548A (rs7799039), leptin receptor (LEPR) A668G (rs1137101) and adiponectin type two receptor (ADIPOR2) G795A (rs16928751) genes. Results. The staff of the main group revealed a higher level of leptin (8.1 (3.7; 14.4) ng/ml) relative to the same indicator in the control group (6.0 (4.1; 11.1) ng/ml), p<0.028. Levels of leptin and adiponectin moderately and weakly correlate with hormonal and metabolic parameters. In the group of employees with less than 10 years of experience, a higher level of adiponectin was established compared to the group with 11–20 years of experience (6.1 (4.6; 9.1) mcg/ml and 4.5 (3.6; 6.4) mcg/ml, respectively); with an increase in work experience of more than 20 years, a significant increase in the concentration of leptin was found (p<0.05). Scientists have identified the significance of single-nucleotide polymorphisms of the LEPR, LEP, ADIPOR2 genes in the development of abdominal obesity, an increase in cholesterol levels and a decrease in the level of total testosterone in workers exposed to electric and magnetic fields of industrial frequency. Limitations. The study is limited to the number of surveyed (144 employees). Conclusion. The results of the study indicate the relationship of biochemical and molecular genetic markers of adipokine metabolism with indicators of hormonal and metabolic disorders in employees exposed to electric and magnetic fields of industrial frequency. When examining workers exposed to electric and magnetic fields of industrial frequency, the use of clinical and laboratory markers of adipokine metabolism (biochemical, molecular genetic) is informative in a comprehensive assessment of cardiovascular risk. Ethics. The work complies with ethical standards developed in accordance with the Helsinki Declaration of the World Medical Association "Ethical Principles of conducting Scientific medical research with human participation" as amended in 2000 and the "Rules of Clinical Practice in the Russian Federation" approved by Order of the Ministry of Health of the Russian Federation No. 200n dated 01.04.2016. Informed consent to participate in the study was received from each of the surveyed, approved in accordance with the established procedure by the local ethics committee of Izmerov Research Institute of Occupational Health (minutes of the meeting of the Ethics committee of Izmerov Research Institute of Occupational Health No. 4 dated 12/25/2013).
Markers of adipokine metabolism and hormonal-metabolic disorders in workers exposed to electric and magnetic fields of industrial frequency
Introduction. With the growth of urbanization processes, the problem of professional exposure to electric and magnetic fields of industrial frequency is an increasingly relevant topic. Recently, the scientists paid a special attention to the long-term health consequences associated with prolonged exposure to harmful physical factors. The previously obtained data on the increase in the levels of lipid metabolism and hormonal and metabolic disorders in workers exposed to electric and magnetic fields of industrial frequency determine the relevance of studying adipokine metabolism and assessing genetic risk factors for predisposition to cardiovascular pathology in employees of the electric power industry. The study aims to research the relationship of biochemical and molecular genetic markers of adipokine metabolism with indicators of hormonal and metabolic disorders for a comprehensive assessment of cardiovascular risk in workers exposed to electric and magnetic fields of industrial frequency. Materials and methods. The researchers examined 144 employees of the main group engaged in the repair and operation of power grid facilities and 40 employees of the control group who are not exposed to electromagnetic fields of industrial frequency.The concentration of leptin and adiponectin was determined in blood serum samples. The authors have calculated the ratio of adiponectin to leptin. We have performed a molecular genetic study of single nucleotide polymorphisms of leptin (LEP) G2548A (rs7799039), leptin receptor (LEPR) A668G (rs1137101) and adiponectin type two receptor (ADIPOR2) G795A (rs16928751) genes. Results. The staff of the main group revealed a higher level of leptin (8.1 (3.7; 14.4) ng/ml) relative to the same indicator in the control group (6.0 (4.1; 11.1) ng/ml), p<0.028. Levels of leptin and adiponectin moderately and weakly correlate with hormonal and metabolic parameters. In the group of employees with less than 10 years of experience, a higher level of adiponectin was established compared to the group with 11–20 years of experience (6.1 (4.6; 9.1) mcg/ml and 4.5 (3.6; 6.4) mcg/ml, respectively); with an increase in work experience of more than 20 years, a significant increase in the concentration of leptin was found (p<0.05). Scientists have identified the significance of single-nucleotide polymorphisms of the LEPR, LEP, ADIPOR2 genes in the development of abdominal obesity, an increase in cholesterol levels and a decrease in the level of total testosterone in workers exposed to electric and magnetic fields of industrial frequency. Limitations. The study is limited to the number of surveyed (144 employees). Conclusion. The results of the study indicate the relationship of biochemical and molecular genetic markers of adipokine metabolism with indicators of hormonal and metabolic disorders in employees exposed to electric and magnetic fields of industrial frequency. When examining workers exposed to electric and magnetic fields of industrial frequency, the use of clinical and laboratory markers of adipokine metabolism (biochemical, molecular genetic) is informative in a comprehensive assessment of cardiovascular risk. Ethics. The work complies with ethical standards developed in accordance with the Helsinki Declaration of the World Medical Association "Ethical Principles of conducting Scientific medical research with human participation" as amended in 2000 and the "Rules of Clinical Practice in the Russian Federation" approved by Order of the Ministry of Health of the Russian Federation No. 200n dated 01.04.2016. Informed consent to participate in the study was received from each of the surveyed, approved in accordance with the established procedure by the local ethics committee of Izmerov Research Institute of Occupational Health (minutes of the meeting of the Ethics committee of Izmerov Research Institute of Occupational Health No. 4 dated 12/25/2013).
The state of the hypothalamic-pituitary-adrenal system in workers exposed to electric and magnetic fields of industrial frequenc
Introduction. Electric and magnetic fields of industrial frequency are an integral part of production processes, and their effect on the human body is of increasing interest both among scientists and among specialists in the field of medicine and occupational safety. In recent decades, there has been growing concern about the potential impact of these areas on the health of workers, especially those who are exposed to prolonged exposure in the course of their professional activities. In this context, we pay special attention to the neuroendocrine system, which plays a key role in regulating many physiological processes, including metabolism, stress reactions and maintaining homeostasis. The study of the fundamentals of the neuroendocrine system and the mechanisms of the effect of electromagnetic fields on the body not only contributes to the deepening of scientific knowledge in the field of biomedical research, but also has practical significance in ensuring occupational safety and improving working conditions in industrial enterprises, allowing to identify possible health consequences and develop effective measures to protect workers from negative bioeffects. The study aims to research the effects of electric and magnetic fields of industrial frequency on the functional state of the hypothalamic-pituitary-adrenal system of employees of electric grid facilities. Materials and methods. Specialists examined 144 employees of the main group engaged in the repair and operation of electric grid facilities and 40 employees of the control group who were not exposed to electromagnetic fields of industrial frequency. We determined the concentration of adrenocorticotropic hormone, cortisol and dehydroepiandrosterone sulfate in blood serum samples and calculated the ratio of dehydroepiandrosterone sulfate to cortisol. Results. Workers exposed to the combined effects of electric and magnetic fields of industrial frequency had a lower (p<0.05) level of adrenocorticotropic hormone (1.9 [0.5; 3.9] pg/ml) and dehydroepiandrosterone sulfate (5.8 [3.7; 8.4] mmol/l) in the blood compared with the group of workers exposed to magnetic fields industrial frequency fields (4.4 [2.1; 12.9] pg/ml; 9.8 [6.3; 14.5] mmol/l) and to the control group (6.4 [4.0; 19.8] pg/ml; 7.8 [4.7; 13.3] mmol/l), respectively. The scientists also revealed in the group of workers exposed to combined exposure in the field, the association of a low ratio of dehydroepiandrosterone sulfate and cortisol with the development of cardiovascular diseases and feedback from work experience (p<0.05). Limitations. The study is limited by the number of people surveyed (144 employees). Conclusion. The results of the study indicate the hypoactivity of the hypothalamic-pituitary-adrenal system induced by exposure to electric and magnetic fields of industrial frequency, manifested by a decrease in the level of adrenocorticotropic hormone, dehydroepiandrosterone sulfate and its relationship to cortisol in workers exposed to combined effects of electric and magnetic fields of industrial frequency. Ethics. The work complies with ethical standards developed in accordance with the Helsinki Declaration of the World Medical Association "Ethical Principles of conducting Scientific medical research with human participation" as amended in 2000 and the "Rules of Clinical Practice in the Russian Federation" approved by Order of the Ministry of Health of the Russian Federation dated 04/01/2016 No. 200n. We received informed consent from each examined person to participate in the study, approved in accordance with the established procedure by the local Ethics Committee of Izmerov Research Institute of Occupational Health (minutes of the meeting of the Ethics Committee No. 17 dated 12/16/2015).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
Contact Info
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Product
Resources
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.
