The Influence of Family History of Type 2 Diabetes Mellitus on Positive Health Behavior Changes among African Americans

Ard, D.; Tettey, Naa-Solo; Feresu, Shinga

doi:10.1155/2020/8016542

Cited by 14 publications

(12 citation statements)

References 19 publications

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“…In a meta-analysis conducted in 2010, the relative risk of developing diabetes in people with a BMI above 30 was 7.19 fold that of people with a BMI below 25 ( 6 ). Other risk factors associated with the disease include obesity, high blood pressure, heart disease, family history, and race ( 7 ). Diabetes brings about variety of microvascular and macrovascular complication in different body organs.…”

Section: Introductionmentioning

confidence: 99%

How Much Excess Body Weight, Blood Pressure, Triglyceride, or Age Can Double the Likelihood of Diabetes Type 2?

Afshar¹,

Najafipour²,

Farokhi³

et al. 2022

ijph

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Background: We aimed to identify the level of known risk factors of diabetes associated with doubled likelihood of diabetes type 2. Methods: In this cross-sectional study, an analysis was performed on the data of 9930 individuals aged 15 yr and older participating from 2014 to 2018 in the second phase of the Kerman coronary artery disease risk factors study (KERCADRS), Kerman, Iran. Data were collected using a standard questionnaire. Multivariable logistic regression was performed to identify factors associated with doubled chance of diabetes. Results: The mean age of participants was 46.1±15.5 yr from which 59.5% were women. Overall, 1105 (11.1%) individuals had type 2 diabetes. An increase of 13.86 yr in age, an increase of 17.32 kg/m2 unit in the amount of body mass index, an increase of 0.17 in the waist-to-hip ratio, a 77 mmHg increase in systolic blood pressure and 6.07 unit increase in triglyceride to HDL ratio doubled the chances of developing type 2 diabetes. Conclusion: Slight changes in the waist-to-hip circumference ratio (0.17), aging (14 yr), and increase in TG/HDL ratio (6.07 unit) were the most important risk factors, while intense physical activity was the most important protective factor associated with doubling of the chances of developing diabetes. Since most of these risk factors are modifiable, increase in physical activity and providing facilities to improve lifestyle in the community seems necessary.

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Section: Introductionmentioning

confidence: 99%

How Much Excess Body Weight, Blood Pressure, Triglyceride, or Age Can Double the Likelihood of Diabetes Type 2?

Afshar¹,

Najafipour²,

Farokhi³

et al. 2022

ijph

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“…Diabetes mellitus is a chronic disease when the pancreas cannot generate enough insulin (Ard et al, 2020). It also occurs when the body is unable to successfully consume the produced insulin (Halim & Halim, 2019).…”

Section: Introductionmentioning

confidence: 99%

The Kinetic Evaluation and DFT Study of Cis-[Pt(Asc)(NH3)2] Complex as an Inhibitor to Type 2 Diabetic Human Amylase

Al-Rawi¹,

Maher²,

Alajrawy³

et al. 2022

JST

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Several metal complexes and organic compounds and extracted herbs that might be involved in the bio-mechanism of the type 2 diabetes mellitus treatments. This research aims to synthesize a new platinum (II) complex and study its kinetics as an inhibitor for freshly purified amylase from type 2 human diabetics. The amylase enzyme was precipitated from diabetic patients. The complex cis-[Pt(Asc)(NH3)2] was synthesized and characterized experimentally and theoretically by DFT calculations to conclude the structure. Both calculations confirmed the square planar geometry for the prepared complex. The results showed that the complex is more stable and polar than the L-ascorbic acid derivative. Therefore, we suggested that the synthesized Pt(II) complex is appropriate to be examined as an inhibitor for the amylase enzyme. Several concentrations from the Pt(II) complex were prepared for kinetic purposes. Kinetic results have shown that the newly prepared complex has a remarkable inhibition effect on the amylase enzyme. Kinetic parameters were fitted using the Lineweaver–Burk plot. The inhibition reaction was confirmed as a non-competitive inhibitor. Also, an inorganic compound derived from vitamin C was prepared and diagnosed by several spectroscopic methods, and a comparison between the experimental and theoretical data was conducted. The DFT study of the prepared complex gave a useful explanation for the complex and its stability. Thus, an inhibitory effect on the activity of the amylase enzyme was clearly shown by the newly prepared Pt(II) complex. It can be concluded that Pt(II) complex could be used as an amylase inhibitor.

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“…Income (Rabi et al, 2006), education (Whitaker et al, 2014), age (Selvin and Parrinello, 2013), gender (Siddiqui, Khan and Carline, 2013), past medical history (Tattersall, 2010), family history (Ard, Tettey and Feresu, 2020), health complication (Abejew, Belay and Kerie, 2015), types of medication (Stubbs, Levy and Dhatariya, 2017) and Spdrt (Lv and Guo, 2020) are associated with diabetes. With age, the body's sugar level may drop, and the disease can be fatal.…”

Section: Introductionmentioning

confidence: 99%

Survival Analysis on Time-To-Recovery of Diabetic Patients at Minlik Referral Hospital, Ethiopia: Retrospective Cohort Study

Belay

Derebew

Abebaw

2021

Preprint

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AimThe study aimed to determine the time to recovery of diabetic patients who have been treated in the hospital under follow-up. Subject and MethodsA retrospective cohort study design was carried out. The fast blood glucose level of diabetic patients who are under follow-up in the hospital was measured from 2016 to 2020. One thousand seven hundred diabetic patients were included in the study. Kaplan-Meier, Log-rank test, global test, Schoenfeld residuals, and Cox-PH model were used for statistical analysis.ResultsOut of the total of 1278 patients, 27.4% were censored (withdrawal from follow-up) and 72.6% recovered from the diabetic disease. For sex, the expected hazard is 1.322 times higher in males than female diabetic patients or there is a 32.2% increase in the expected hazard in males relative to female diabetic patients. For Spdrt, The expected hazard is 1.164 times higher in the patients who had taken leute than diabetic patients who took doanied. For regimen, the expected hazard is 1.495 times higher in the patients who had been treated by insulin agent only than diabetic patients who were treated by oral agents only ConclusionThe intensive-therapy regimen, Spdrt, and gender differences were statistically significant and critically contribute to the survival time to recovery of diabetic patients.

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The Influence of Family History of Type 2 Diabetes Mellitus on Positive Health Behavior Changes among African Americans

Cited by 14 publications

References 19 publications

How Much Excess Body Weight, Blood Pressure, Triglyceride, or Age Can Double the Likelihood of Diabetes Type 2?

How Much Excess Body Weight, Blood Pressure, Triglyceride, or Age Can Double the Likelihood of Diabetes Type 2?

The Kinetic Evaluation and DFT Study of Cis-[Pt(Asc)(NH3)2] Complex as an Inhibitor to Type 2 Diabetic Human Amylase

Survival Analysis on Time-To-Recovery of Diabetic Patients at Minlik Referral Hospital, Ethiopia: Retrospective Cohort Study

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