The Influence of Intra-Arterial Chemotherapy on Local Control of Bone Sarcoma

Marsden, W.; Stephens, Frederick O.; Tattersall, Martin H. N.; McCarthy, Stanley W.; Waugh, Richard

doi:10.1007/978-4-431-68072-7_30

Cited by 6 publications

(3 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…16,17322 The resolution of the surrounding reactive zone, the hardening, and in some cases, shrinkage of the extra-osseous tumour mass are of great help to the surgeon in extending this threshold, for all situations. The doubts about criteria for diagnosis are also evident but the result is eventually the same.…”

Section: Discussionmentioning

confidence: 99%

“…The local effects of intra-arterial chemotherapy have been described in previously published studies from the Royal Prince Alfred Hospital. 16,17322 The resolution of the surrounding reactive zone, the hardening, and in some cases, shrinkage of the extra-osseous tumour mass are of great help to the surgeon in extending this threshold, for all situations. There is a commitment to the use of intraarterial chemotherapy if the resection margin is likely to be critical.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Osteosarcoma: Then and Now. A Fifty Year Review at Royal Prince Alfred Hospital

Marsden

Sharland

1992

Australian and New Zealand Journal of Surgery

View full text Add to dashboard Cite

The purpose of this study is to review survival, treatment methods and criteria for diagnosis of osteosarcoma at Royal Prince Alfred Hospital during two periods in the last 50 years. The records of 22 patients diagnosed with osteosarcoma and nine with osteosarcoma in Paget's disease (from 1939 to 1950) were reviewed. All but one had died within three years. One patient survived six years. The second series was taken from 1983 to 1990. Forty-nine patients, including three with Paget's sarcoma, were studied. Probability of surivival was estimated by actuarial analysis using Kaplan-Meier curves. Overall survival was estimated at 45%. Those patients who were free of metastatic disease at the conclusion of their treatment were estimated to have a probability of survival of 85%.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Osteosarcoma: Then and Now. A Fifty Year Review at Royal Prince Alfred Hospital

Marsden

Sharland

1992

Australian and New Zealand Journal of Surgery

View full text Add to dashboard Cite

show abstract

“…Hardening, with or without encapsulation, makes the tumour more easily defined for the surgeon. Resection of a tumour with an adequate margin is easier after such a response to treatment (Marsden et al 1989. This in tum has a significant impact on the level of function achievable for these patients and, consequently, on improved quality of life.…”

Section: Induction Treatmentmentioning

confidence: 99%