The Influence of Intraoperative Central Venous Pressure on Delayed Graft Function in Renal Transplantation: A Single-Center Experience

Bacchi, Giuliana; Buscaroli, Andrea; Fusari, Maurizio; Neri, Luca; Cappuccilli, Maria; Carretta, Elisa; Stefoni, Sergio

doi:10.1016/j.transproceed.2010.08.042

Cited by 57 publications

(47 citation statements)

References 27 publications

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“…Although a high CVP can decrease the glomerular filtration rate, a low CVP can also result in kidney injury because low CVP can decrease the fluid volume and cardiac output. One study found that CVP of less than 8 mmHg and intraoperative fluid administration of less than 2,250 mL were risk factors for delayed kidney graft function (11). Thus, it is necessary to monitor for a reduction in cardiac output in patients with decreased CVP with reduced fluid volume.…”

Section: Discussionmentioning

confidence: 99%

“…According to the mean CVP over 7 days, the enrolled cases were divided into three groups: low (<8 mmHg), normal (8)(9)(10)(11)(12), and high CVP (>12 mmHg). According to whether CVP dropped to less than 8 mmHg during 7 days, the enrolled cases were divided into two groups: CVP dropped to less than 8 mmHg and CVP did not drop to less than 8 mmHg.…”

Section: Methodsmentioning

confidence: 99%

“…In recent years, studies of the effects of CVP on organ function or prognosis have generally been carried out on patients with heart failure (2)(3)(4)(5)(6)(7), with few studies on patients with septic shock. Moreover, the consecutive changes of CVP and organ function cannot be expressed in detail because of less time points in previous studies (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)17,18).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Central Venous Pressure Dropped Early is Associated with Organ Function and Prognosis in Septic Shock Patients

Wang

Yao

Liu

et al. 2015

Shock

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Central Venous Pressure Dropped Early is Associated with Organ Function and Prognosis in Septic Shock Patients

Wang

Yao

Liu

et al. 2015

Shock

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show abstract

“…9 In addition, the transplanted kidney function might be delayed, thus leading to the need for postoperative dialysis. If the patient has no arterioevenous (AV) fistula a dialysis line is required, which can also be used to measure CVP.…”

Section: Perioperative Anaesthetic Managementmentioning

confidence: 99%

Anaesthesia for renal transplantation: an update

Bennett

Pace

2015

Anaesthesia & Intensive Care Medicine

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“…However, other studies have shown either a lack of effect or a lower CVP to be acceptable [14][15][16][17] . Additionally, systolic blood pressure (SBP) should probably be maintained above 120 mmHg, while mean arterial pressures (MAP) should be above 90 mmHg 16,18,19 .…”

Section: Introductionmentioning

confidence: 99%

Living Kidney Transplant: The Influence of Intra-Operative Hemodynamics on Delayed Graft Function

Schutt

Case

Barrick

et al. 2017

JOT

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Purpose: Intra-operative insults may subject living kidney transplants to poor outcomes. Therefore, we investigated whether intra-operative recipient and donor hemodynamics could act as predictors of delayed graft function and subsequent outcomes. Materials and Methods:Living kidney donors and recipients from 2010-2016 at this institution underwent a retrospective chart review. Graft function by post-operative day 7 was used to classify recipients as delayed graft function (need for dialysis), slow graft function (creatinine > 2.5) and good function. Groups were analyzed for intra-operative hemodynamic differences and at one year, incidence of rejection, graft function and survival were compared.Results: A total of 111 living renal transplants were performed. Average recipient age was 50 and just over half were male (53%). 9% (n=10) and 10% (n=11) developed delayed graft function and slow graft function, respectively. Minimum recipient post re-perfusion central venous pressure ≥12 mmHg was associated with poor graft function (delayed graft function/slow graft function/good function=67%/56%/24%, p=0.009), while intra-operative hypotension (systolic <90 mmHg or diastolic <50 mmHg) was not. Delayed graft function and slow graft function had higher incidences of rejection than good function (30% and 36% vs 9%, p=0.012).Graft function and survival were similar. One patient died with a functioning graft. Conclusions:This single center retrospective study suggests that a post re-perfusion central venous pressure ≥12 mmHg is associated with delayed graft function.

show abstract

The Influence of Intraoperative Central Venous Pressure on Delayed Graft Function in Renal Transplantation: A Single-Center Experience

Cited by 57 publications

References 27 publications

Central Venous Pressure Dropped Early is Associated with Organ Function and Prognosis in Septic Shock Patients

Central Venous Pressure Dropped Early is Associated with Organ Function and Prognosis in Septic Shock Patients

Anaesthesia for renal transplantation: an update

Living Kidney Transplant: The Influence of Intra-Operative Hemodynamics on Delayed Graft Function

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