Objectives-To examine gender-differentiated health and cognitive/motor/language developmental outcomes among medically at-risk infants.
Design-Longitudinal descriptive and comparative secondary analysis.
Setting-Neonatal intensive care unit, intermediate care unit, and infectious disease clinic of the tertiary medical centers in the Southeast and East United States.Participants-One hundred eight (108) premature infants, 67 medically fragile infants, and 83 infants seropositive for HIV.Methods-Neonatal and later health variables were obtained from the medical record to determine the technology dependence scores and frequency of common health problems. Data for physical growth and cognitive/motor/language development were obtained through the physical measurement, including the Bayley Scales of Infant Development-Second Edition, the Vineland Adaptive Behavior Scale, the Toll Control Developmental Checklist, and the Preschool Language Scale-3 during home visits between 6 to 27 months corrected ages.Results-Fewer effects on health and developmental outcomes related to gender were observed with medically fragile infants than the other two groups of infants. The cognitive/motor/language scores were decreased with increasing age of the infants in all groups.Conclusion-Male gender can be considered a significant biological risk factor for infants' cognitive and motor development, especially for premature infants. Because of their increased risk, it is recommended that male infants who are born prematurely or seropositive for HIV have early and advanced developmental screening tests by trained personnel through periodic pediatric clinic.
KeywordsGender; Health and Development; Premature Infants; Medically Fragile Infants; Infants Seropositive for HIV Corresponding Information: June Cho, PhD, RN, School of Nursing, University of Alabama at Birmingham, NB 428B, 1530 3rd Ave. S., Birmingham, AL 35294 USA, jcho@uab.edu.
NIH Public AccessAuthor Manuscript J Obstet Gynecol Neonatal Nurs. Author manuscript; available in PMC 2011 September 1.
NIH-PA Author ManuscriptNIH-PA Author Manuscript
NIH-PA Author ManuscriptGender has been found to be a significant predictor of health and development in childhood, with boys usually showing greater vulnerability (Gissler, Järvelin, Louhiala, & Hemminkj, 1999;Hintz et al., 2006;James, 2000;Nuñez & McCarthy, 2003;Stevenson et al., 2000;Tioseco, Aly, Essers, Patel, & El-Mohandes, 2006). Gender differences in health appear early; boys are more likely to be born prematurely than are girls and tend to have more neonatal complications (Cooperstock, Bakewell, Herman, & Schramm, 1998;Gissler et al.;Hintz et al.;James, 2000). The higher rate of male preterm births occurs in both singleton and multiple births (Cooperstock et al.) as well as in White and Black births (Cooperstock & Campbell, 1996). In comparison with girls, boys also are more likely to be intubated, receive more resuscitation medications, and have an approximately 20% higher risk for low 1-and 5-min Apgar scores (Bekedam, En...