The Influence of Noncognitive Factors on the Mini-Mental State Examination in Older Mexican-Americans

Black, Sandra A.; Espino, David V.; Mahurin, Roderick K.; Lichtenstein, Michael J.; Hazuda, Helen P.; Fabrizio, Dennis; Ray, L.; Markides, Kyriakos S.

doi:10.1016/s0895-4356(99)00100-6

Cited by 133 publications

(87 citation statements)

References 30 publications

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“…Na primeira adaptação do MEM 5 , observou-se grande influência da escolaridade sobre o desempenho no teste, fato este constatado em outros estudos brasileiros como de Almeida et al 21 , Caramelli et al 22 , e reproduzindo efeito amplamente constatado na literatura disponí-vel sobre o teste [6][7][8][9][10][11][12][13][14][15][17][18][19] .…”

Section: Discussionunclassified

“…Em nosso meio, na primeira versão publicada por Bertolucci et al 5 foi observada clara e forte influên-cia da escolaridade sobre os escores totais do MEM, replicando resultados de trabalhos anteriores em outras populações, em que também se constataram escores menores em indivíduos com níveis educacionais mais baixos [6][7][8][9][10][11][12][13][14][15][16][17][18] . No estudo foi observado que vários sub-itens do MEM sofriam influência da es-colaridade, tais como as orientações temporal e espacial, atenção, leitura, cópia dos pentágonos e escrita 19 .…”

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Sugestões para o uso do mini-exame do estado mental no Brasil

Brucki

Nitrini

Caramelli

et al. 2003

Arq. Neuro-Psiquiatr.

2,021

1,096

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RESUMO -Modificações no mini-exame do estado mental (MEM) foram sugeridas anteriormente em nosso meio. Neste artigo relatamos sugestões para aplicação uniforme deste instrumento. Método: Avaliamos 433 indivíduos saudáveis sem queixas de memória através do MEM tendo seu desempenho sido avaliado quanto às variáveis demográficas. As modificações propostas foram detalhadamente descritas. Resultados: A escolaridade foi o principal fator que influenciou o desempenho dos indivíduos. Na análise de variância entre os grupos de escolaridade obtivemos F(4,425)=100,45, p<0,0001. Os escores medianos por escolaridade foram: para analfabetos, 20; para idade de 1 a 4 anos, 25; de 5 a 8 anos, 26,5; de 9 a 11 anos, 28; para indivíduos com escolaridade superior a 11 anos, 29. Conclusão: Sugerimos o uso desta versão para uniformização dos resultados em nosso meio. Sua aplicabilidade revelou-se boa para ambientes hospitalar, ambulatorial e para estudo populacionais.PALAVRAS-CHAVE: mini-exame do estado mental, testes de rastreio, educação, ambiente domiciliar, ambiente hospitalar.Suggestions for utilization of the mini-mental state examination in Brazil Suggestions for utilization of the mini-mental state examination in Brazil Suggestions for utilization of the mini-mental state examination in Brazil Suggestions for utilization of the mini-mental state examination in Brazil Suggestions for utilization of the mini-mental state examination in Brazil ABSTRACT -Mini-metal state examination (MMSE) is a screening test to detect cognitive impairment. The objectives of the present study are to describe some adaptations for use of MMSE in Brazil and to propose rules for its uniform application. Method: We evaluated 433 healthy subjects using the MMSE and verified the possible influence of demographic variables on total scores. Results: Educational level was the main factor that influenced performance, demonstrated by ANOVA: F(4,425) = 100.45, p<0.0001. The median values for educational groups were: 20 for illiterates; 25 for 1 to 4 yrs; 26.5 for 5 to 8 yrs; 28 for 9 to 11 yrs and 29 for higher levels. Conclusion: The MMSE is an excellent screening instrument and definitive rules are necessary for comparison purposes.

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Section: Discussionunclassified

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Sugestões para o uso do mini-exame do estado mental no Brasil

Brucki

Nitrini

Caramelli

et al. 2003

Arq. Neuro-Psiquiatr.

2,021

1,096

View full text Add to dashboard Cite

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“…Many studies have tried to adjust new cut-off scores for the MMSE according to educational leve l 5 , 1 2 -1 4 . However, lowering the threshold on any instrument increases the risk of false negatives 6 . Although different education adjusted MMSE cut-off scores are an important move toward recognizing cognitive impairment within large samples in the community in developing countries where illiteracy is still a problem, our data suggest that screening for functional impairment may strengthen the suspicion of dementia.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of cognitive and functional impairment in community-dwelling elderly: importance of evaluating activities of daily living

Laks

Batista²,

Guilherme³

et al. 2005

Arq. Neuro-Psiquiatr.

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Illiteracy and poor schooling is still a major problem in developing countries. As life expectancy is increasing steadily, these countries have many illiterate elderly at risk of developing dementia. In fact, illiteracy has been considered a risk factor for dementia, along with age, female gender, and living cional (analfabetos/alfabetizados: OR=15,60; p=0/ OR = 16,40; p=0). Idade e gênero são fatores associados a comprometimento cognitivo/funcional (p<0,05). A prevalência de comprometimento cognitivo/funcional é mais alta que a encontrada em outro estudo brasileiro. Idade, gênero feminino e comprometimento funcional estão diretamente associados a comprometimento cognitivo. O reconhecimento de comprometimento funcional pode ser mais fácil por familiares/profissionais de saúde. Isso reforça a idéia do uso combinado de escalas em rastreamentos de demência. PREVALENCE OF COGNITIVE AND FUNCTIONAL IMPAIRMENT IN COMMUNITY-DWELLING ELDERLYPA L AV R A S -C H AVE: Status funcional, comprometimento cognitivo, epidemiologia, prevalência, fatores de risco

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“…We analyzed MMSE as a continuous outcome as well as according to categories based on previously defined MMSE thresholds [15]: MMSE score ≥24 (normal) and MMSE score <24 (cognitive impairment).…”

Section: Methodsmentioning

confidence: 99%

The rs1277306 Variant of the <b><i>REST</i></b> Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population

Lin

Tsai

Kuo

et al. 2017

Dement Geriatr Cogn Disord

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Background/Aims: There is growing evidence that the RE1-silencing transcription factor (REST) gene may contribute to cognitive aging and Alzheimer diseases. In this replication study, we reassessed whether single nucleotide polymorphisms (SNPs) within the REST gene are linked with cognitive aging independently and/or through complex interactions in an older Taiwanese population. Methods: A total of 634 Taiwanese subjects aged over 60 years from the Taiwan Biobank were analyzed. Mini-Mental State Examination (MMSE) scores were performed for all subjects to weigh cognitive functions. Results: Our data showed that the REST rs1277306 SNP was significantly associated with cognitive aging among all subjects (p = 0.0052). Furthermore, the association remained significant for individuals without APOE ε4 allele (p = 0.0092), but not for individuals with at least 1 APOE ε4 allele. This association remained significant after Bonferroni correction. Additionally, we found the interactions between the rs1713985 and rs1277306 SNPs on cognitive aging (p = 0.016). However, the 3-marker haplotype derived from the rs1713985, rs3796529, and rs7680734 SNPs in the REST gene demonstrated no association with cognitive aging. Conclusion: Our study indicates that the REST gene may contribute to susceptibility to cognitive aging independently as well as through SNP-SNP and APOE-REST interactions.

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The Influence of Noncognitive Factors on the Mini-Mental State Examination in Older Mexican-Americans

Cited by 133 publications

References 30 publications

Sugestões para o uso do mini-exame do estado mental no Brasil

Sugestões para o uso do mini-exame do estado mental no Brasil

Prevalence of cognitive and functional impairment in community-dwelling elderly: importance of evaluating activities of daily living

The rs1277306 Variant of the <b><i>REST</i></b> Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population

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