The Influence of Obesity and Overweight on Hip Bone Mineral Density in Lebanese Women

Hage, Rawad El; Bachour, Falah; Khairallah, Walid; Bedran, Farid; Maalouf, Naim M.; Zakhem, Eddy; Issa, Majed; Adib, Gemma; Maalouf, Ghassan

doi:10.1016/j.jocd.2013.03.015

Cited by 25 publications

(8 citation statements)

References 8 publications

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“…The TBS score can assist the healthcare professional in assessing fracture risk (20,21). In our laboratory, the coefficients of variation were less than 1% for BMC and BMD and less than 3% for FN CSA (22)(23)(24)(25). The same certified technician performed all analyses using the same technique for all measurements.…”

Section: Bone Variablesmentioning

confidence: 95%

The Relationships Between Skeletal Muscle Index and Bone Variables in a Group of Young Adults

Khawaja

Sabbagh

Prioux

et al. 2021

Journal of Clinical Densitometry

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HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

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Section: Bone Variablesmentioning

confidence: 95%

The Relationships Between Skeletal Muscle Index and Bone Variables in a Group of Young Adults

Khawaja

Sabbagh

Prioux

et al. 2021

Journal of Clinical Densitometry

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“…The association of BMI ≥ 50 kg/m 2 with lower total vertebral column and hip BMD is relevant. It is particularly relevant because there is a hypothesis that the mechanical overload of obesity can increase bone mass [ 7 ]. Our findings corroborate with the physiological pathway in which inflammatory and endocrine factors present in obesity and, more specifically, related to visceral adipose tissue and higher percentage of fat, can compromise the quality of bone mass [ 2 , 3 , 13 , 44 , 68 , 69 , 72 ].…”

Section: Discussionmentioning

confidence: 99%

“…Few studies showed beneficial effects of obesity on bone health. There are reasons to believe that these effects of obesity on BMD are context-dependent, since, in general, excess body fat exerts mechanical overload on the bones, in addition to hyperinsulinemia and hyperamylinemia that may negatively affect the bones [ 7 , 8 , 9 ]. A study revealed that a body mass index (BMI) greater than 40 kg/m 2 had a beneficial effect on BMD [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Bone Mineral Density in Severely Obese Women: Health Risk and Health Protective Risk Factors in Three Different Bone Sites

Cardoso

Peixoto

Rodrigues

et al. 2020

IJERPH

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Factors associated with bone mineral density (BMD) are poorly known in severely obese individuals i.e., a body mass index (BMI) > 35 kg/m2. The objectives of this study were to describe the bone health profile of severely obese Brazilian women, to identify the health risk and health protective factors for BMD in this group and to assess whether these factors vary according to three different bone sites. BMD was assessed using dual-energy X-ray absorptiometry (DXA). This study analyzed baseline data from 104 women who had an average BMI of 43.7 ± 4.5 kg/m2 and presented the following BMD status: 1.283 ± 0.094 g/cm2 for total body, 1.062 ± 0.159 g/cm2 for vertebral column and 1.195 ± 0.134 g/cm2 for hip. They took part in the “Effect of nutritional intervention and olive oil in severe obesity” randomized clinical trial (DieTBra Trial). The risk factors negatively associated with lower BMD were age ≥50 years for the three bone sites i.e., total body, vertebral column and hip. Smoking for total body BMD (p = 0.045); BMI ≥ 50kg/m2 for vertebral column and hip; menopause for hip; high C-reactive protein (CRP) levels (p = 0.049), insufficient zinc (p = 0.010) and previous fracture for vertebral column (p = 0.007). The protective factors positively associated with BMD were physical activity (≥150 min/week (p = 0.001)) for hip; type 2 diabetes mellitus (DM2) (p < 0.0001) total body and adequate vitamin D levels from food consumption (p = 0.039) for vertebral column. A BMI ≥ 50 kg/m2 was a risk factor for lower BMD. The findings showed that protective and risk factors varied by bone site. The original study is registered with ClinicalTrials.gov. (protocol number: NCT02463435).

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“…Both bone parameters were determined for each individual by DXA at whole body, lumbar spine and proximal femur (total hip [TH] and FN). In our laboratory, the coefficients of variation were < 1% for BMC and BMD [25][26][27][28]. All analyses were performed by the same certified technician who used the exact same technique for all measurements.…”

Section: Measurements Of Bone Variablesmentioning

confidence: 99%

Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women

et al. 2020

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Background: The current study's purpose is to compare hip structural analysis variables in a group of postmenopausal women with sarcopenia and another group of postmenopausal women with normal skeletal muscle mass index. To do so, the current study included 8 postmenopausal women (whose ages ranged between 65 and 84 years) with sarcopenia and 60 age-matched controls (with normal skeletal muscle mass index (SMI)). Body composition and bone parameters were evaluated by dual-energy X-ray absorptiometry (DXA). Results: Weight, lean mass, body mass index, femoral neck cross-sectional area (FN CSA), FN section modulus (Z), FN cross sectional moment of inertia (CSMI), intertrochanteric (IT) CSA, IT Z, IT CSMI, IT cortical thickness (CT), femoral shaft (FS) CSA, FS Z and FS CSMI were significantly greater (p < 0.05) in women with normal SMI compared to women with sarcopenia. In the whole population, SMI was positively associated with IT CSA, IT Z, IT CSMI, IT CT, FS CSA, FS Z, FS CSMI, FS CT but negatively correlated to IT buckling ratio (BR) and FS BR. Conclusion: The current study suggests that sarcopenia has a negative effect on hip bone strength indices in postmenopausal women.

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The Influence of Obesity and Overweight on Hip Bone Mineral Density in Lebanese Women

Cited by 25 publications

References 8 publications

The Relationships Between Skeletal Muscle Index and Bone Variables in a Group of Young Adults

The Relationships Between Skeletal Muscle Index and Bone Variables in a Group of Young Adults

Bone Mineral Density in Severely Obese Women: Health Risk and Health Protective Risk Factors in Three Different Bone Sites

Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women

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