The influence of size on the toxicity of an encapsulated pesticide: a comparison of micron- and nano-sized capsules

Meredith, Alicea N.; Harper, Barbara; Harper, Stacey L.

doi:10.1016/j.envint.2015.10.012

Cited by 62 publications

(39 citation statements)

References 39 publications

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“…17 )). Most nano-enabled agrochemicals exceed the size threshold of 100 nm whereas commercial formulations can unintentionally contain entities <100 nm, 4 , 18 , 19 which illustrates the difficulties associated with defining nanopesticides solely based on a size criterion.…”

Section: Resultsmentioning

confidence: 99%

Environmental fate of nanopesticides: durability, sorption and photodegradation of nanoformulated clothianidin

Kah

Walch

Hofmann

2018

Environ. Sci.: Nano

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Section: Resultsmentioning

confidence: 99%

Environmental fate of nanopesticides: durability, sorption and photodegradation of nanoformulated clothianidin

Kah

Walch

Hofmann

2018

Environ. Sci.: Nano

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“…Thus, complicating the use of hydrophobicity metrics to predict their fate and toxicity. Determining how carrier size influences the hydrophobicity (KOW) and soil sorption (Kd) of a given pesticide, and thus its mobility through soil and water, is important to our understanding of whether the current pesticide's toxicity risk assessments are sufficient to protect against products that incorporate nano-encapsulation technology (Meredith et al, 2016;Slattery et al, 2019).…”

Section: Nano-capsulesmentioning

confidence: 99%

“…67760-104-53883) with 5.9% γ-cyhalothrin; and an EPA registered capsule suspension insecticide with 22.8% λ-cyhalothrin (EPA Reg. Number 100-1,295, Greensboro, NC, USA) are two examples of nano-pesticides currently available in the market under this reformulation scheme (Meredith et al, 2016;Slattery et al, 2019).…”

Section: Drug Delivery Systems In the Agriculturementioning

confidence: 99%

Nanoscale Drug Delivery Systems: From Medicine to Agriculture

Vega-Vásquez

Mosier

Irudayaraj

2020

Front. Bioeng. Biotechnol.

215

107

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The main challenges in drug delivery systems are to protect, transport and release biologically active compounds at the right time in a safe and reproducible manner, usually at a specific target site. In the past, drug nano-carriers have contributed to the development of precision medicine and to a lesser extent have focused on its inroads in agriculture. The concept of engineered nano-carriers may be a promising route to address confounding challenges in agriculture that could perhaps lead to an increase in crop production while reducing the environmental impact associated with crop protection and food production. The main objective of this review is to contrast the advantages and disadvantages of different types of nanoparticles and nano-carriers currently used in the biomedical field along with their fabrication methods to discuss the potential use of these technologies at a larger scale in agriculture. Here we explain what is the problem that nano-delivery systems intent to solve as a technological platform and describe the benefits this technology has brought to medicine. Also here we highlight the potential drawbacks that this technology may face during its translation to agricultural applications, based on the lessons learned so far from its use for biomedical purposes. We discuss not only the characteristics of an ideal nano-delivery system, but also the potential constraints regarding the fabrication including technical, environmental, and legal aspects. A key motivation is to evaluate the potential use of these systems in agriculture, especially in the area of plant breeding, growth promotion, disease control, and post-harvest quality control. Further, we highlight the importance of a rational design of nano-carriers and identify current research gaps to enable scale-up relevant to applications in the treatment of plant diseases, controlled release of fertilizers, and plant breeding.

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“…However, only a small difference was observed, and no statistical analysis was conducted. On the other hand, Meredith et al [56] observed a decrease in toxicity effects on zebrafish with hollow polymeric shell nanoparticle-encapsulated λ-cyhalothrin, and the larger micron-sized particles of the same composition, when compared to the unformulated insecticide λ-cyhalothrin. Oliveira et al [66] also observed a decrease in toxicity in mouse fibroblast cell lines when treated with zein nanoparticle-encapsulated botanical repellents, compared to the botanical repellents alone.…”

Section: Nanoparticles As Carriers For Insecticidesmentioning

confidence: 99%

Nanotechnology for Plant Disease Management

et al. 2018

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Each year, 20%–40% of crops are lost due to plant pests and pathogens. Existing plant disease management relies predominantly on toxic pesticides that are potentially harmful to humans and the environment. Nanotechnology can offer advantages to pesticides, like reducing toxicity, improving the shelf-life, and increasing the solubility of poorly water-soluble pesticides, all of which could have positive environmental impacts. This review explores the two directions in which nanoparticles can be utilized for plant disease management: either as nanoparticles alone, acting as protectants; or as nanocarriers for insecticides, fungicides, herbicides, and RNA-interference molecules. Despite the several potential advantages associated with the use of nanoparticles, not many nanoparticle-based products have been commercialized for agricultural application. The scarcity of commercial applications could be explained by several factors, such as an insufficient number of field trials and underutilization of pest–crop host systems. In other industries, nanotechnology has progressed rapidly, and the only way to keep up with this advancement for agricultural applications is by understanding the fundamental questions of the research and addressing the scientific gaps to provide a rational and facilitate the development of commercial nanoproducts.

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The influence of size on the toxicity of an encapsulated pesticide: a comparison of micron- and nano-sized capsules

Cited by 62 publications

References 39 publications

Environmental fate of nanopesticides: durability, sorption and photodegradation of nanoformulated clothianidin

Environmental fate of nanopesticides: durability, sorption and photodegradation of nanoformulated clothianidin

Nanoscale Drug Delivery Systems: From Medicine to Agriculture

Nanotechnology for Plant Disease Management

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