Background: Starting college or university is a significant life event that can impact students’ physical activity (PA). Social support specific to PA (SSPA) is a social determinant of PA among college and university students. This review had 3 aims: (1) to systematically review studies examining the association between SSPA and PA among students; (2) to examine whether potential associations differed in terms of types or sources of SSPA; and (3) to examine whether any potential associations differed in terms of gender. Methods: Studies were identified using Academic Search Premier, PsycInfo, Sociological Abstracts, and SPORTDiscus. Results: This review included 25 papers. The results suggested that there is a positive association between SSPA and PA among college and university students. Although the importance of different sources of SSPA is not clear, the results suggested that family and friends provide significant SSPA. Conclusions: High variability in measurement methods made it difficult to compare studies and to come to a clear consensus. However, the findings suggested that SSPA may be a determinant of PA. In order to better understand the relationship between SSPA and PA among students, some elements, such as gender, socioeconomic level, and off- or on-campus housing, should be considered in future studies.