The Influence of Ventilation Mode (Spontaneous Ventilation, IPPV and PEEP) on Cardiopulmonary Parameters in Sevoflurane Anaesthetized Dogs

Polis, Ingeborgh; Gasthuys, Frank; Laevens, Hans; Ham, Luc Van; Rick, A. De

doi:10.1046/j.1439-0442.2001.00394.x

Cited by 10 publications

(23 citation statements)

References 34 publications

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“…However, in spontaneous ventilation, arterial oxygen pressure (PaO 2 ) decreases with time 4 . Polis et al 3 reported that, spontaneous ventilation in dogs increased PaCO 2 , while mechanical ventilation significantly decreased this value and that the pH level increased. The same authors stated that neither of these two ventilation methods caused a significant difference in PaO 2 values.…”

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confidence: 98%

“…Spontaneous respiration leads to hypoventilation, which causes hypercapnia, hypoxaemia and changes in the acid-base balance [2][3][4][5] .…”

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confidence: 99%

“…It supports lung function by eliminating carbondioxide and allowing oxygenisation of arterial blood. It increases tidal volume and enables atelectatic alveoli to regain their function 2,3,[5][6][7] .…”

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confidence: 99%

“…Over-inflation of the alveoli leads to formation of pulmonary interstitial emphysema, pneumomediastinum and pneumothorax 6,8 . Due to increasing thoracic pressure, right ventricular dysfunction, altered left ventricular distensibility and low cardiac output, IPPV decreases venous return to the heart 2,3,5,6,9 .…”

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confidence: 99%

“…It leads to respiratory depression and formation of apnoea. In dogs, immediately after propofol injection, PaO 2 values decrease due to hypoventilation 3,11 .…”

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Comparison of the Effects of Spontaneous and Mechanical Ventilation on Blood Gases During General Anaesthesia in Dogs

Güzel¹,

Yıldar²,

Karabağli³

et al. 2013

Kafkas Univ Vet Fak Derg

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SummarySpontaneous ventilation during general anaesthesia leads to respiratory depression and atelectasis. Mechanical ventilation increases tidal volume and eliminates atelectasis. The study material consisted of a total of 20 dogs of different breed, age and gender. Dogs were divided into two groups, consisted of 10 dogs. The first group was established as the spontaneous ventilation (SV) group, while the second group was the mechanical ventilation (MV) group. For induction of anaesthesia, propofol was administered to both groups via intravenous injection at a dose of 6 mg/kg. Blood samples were collected from all dogs in 5 minutes after propofol administration. This period was determined as Minute 0 (T 0 ). In both groups, inhalation anaesthesia was continued with isoflurane. Venous blood samples were collected from dogs in the SV and MV groups at 15 (T 15 ), 30 (T 30 ) and 60 (T 60 ) minutes. Heart rate, respiratory rate, SpO 2 , body temperature and blood gases were monitored. Statistical evaluation of the study was carried out using the Repeated Measures Analysis of Variance method. The results obtained showed that there was no statistically significant difference between the SV and MV groups regarding the examined parameters. However, in the assessments within the group, results obtained from the dogs in the MV group were more reliable from the point of view of the patients remaining stable throughout anaesthesia. Keywords: Spontaneous ventilation, Mechanical ventilation, Blood gases, Dog Köpeklerde Genel Anestezi Sürecinde Spontan ve Mekanik Ventilasyonun Kan Gazları Üzerine Etkilerinin Karşılaştırılması ÖzetGenel anestezide spontan ventilasyon, solunumun baskılanmasına ve atelektaziye yol açar. Mekanik ventilasyon tidal volümü artırır ve atelektaziyi giderir. Çalışma materyalini, farklı ırk, yaş ve cinsiyetteki toplam 20 köpek oluşturdu. Olgular, her grupta 10 köpek olacak şekilde 2'ye ayrıldı. İlk grup spontan ventilasyon (SV), ikinci grup mekanik ventilasyon (MV) grubu olarak belirlendi. Anestezi indüksiyonunda her iki gruba, propofol 6 mg/kg'dan intravenöz enjeksiyonla verildi. Tüm köpeklerden, propofol enjeksiyonunu takip eden 5. dakikada kan örnekleri alındı. Bu süre 0. dakika (T 0 ) olarak değerlendirildi. Her iki grubun inhalasyon anestezisi izofloranla sürdürüldü. SV ve MV grubundaki olgulardan 15. dakika (T 15 ), 30. dakika (T 30 ) ve 60. dakika (T 60 )'larda venöz kan örnekleri alındı. Kalp atım sayısı, solunum sayısı, SpO 2 , vücut ısısı ve kan gazları monitörize edildi. Çalışmanın istatistiki değerlendirmesi Tekrarlı Ölçüm Varyans Analizi metodu ile yapıldı. Elde edilen bulgular, incelenen parametreler yönünden SV ve MV grupları arasında istatistiki anlamda önemli bir fark olmadığını gösterdi. Ancak grup içi değerlendirmelerde, MV grubundaki köpeklerden elde edilen sonuçların, hastaların anestezi süresince stabil kalmaları açısından daha güvenilir olduğu sonucuna ulaşıldı.

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confidence: 98%

“…Spontaneous respiration leads to hypoventilation, which causes hypercapnia, hypoxaemia and changes in the acid-base balance [2][3][4][5] .…”

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

“…It leads to respiratory depression and formation of apnoea. In dogs, immediately after propofol injection, PaO 2 values decrease due to hypoventilation 3,11 .…”

mentioning

confidence: 99%

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