Single-domain YBa 2 Cu 3 O 7−δ (YBCO) superconductors with different additions of Nb 2 O 5 have been fabricated by a modified top seeded infiltration growth (TSIG) process. The growth morphology, microstructure and levitation force were investigated in details. The experimental results reveal that Nb 2 O 5 can react with precursor powders in the TSIG process and finally form nanometer Y 2 Ba 4 CuNbO x (YNb2411) particles which can act as effective flux pinning centers. The content addition of Nb 2 O 5 has sensitive effect on microstructure and superconductive property of YBCO bulks The levitation force increases firstly from 30 to 36 N and then reduces down to 21 N with the increasing of Nb 2 O 5 additions from 0.1 to 0.9 wt% and 1.5 wt%. These results indicate a high-efficient method to improve the properties of YBCO bulks.