The Influential Factors on Antibacterial Behaviour of Copper and Silver Nanoparticles

Abstract

The synthesis of metallic nanoparticles (NPs) is of high interest due to their wide range of applications in various fields. Among various types of NPs, copper and silver NPs have received considerable attention because of their unique chemical, physical and antibacterial properties and also their vast applications in various fields including electronics, optics and medicine. The antibacterial properties of these NPs are the main reason for their application in medicine, textile, water treatment and food industry. Previous studies have shown that several factors like size, shape, type of coating, the concentration of a solution containing silver and copper NPs, type of microorganisms, stability of the solution and also environmental conditions like: pH, the presence of ligand (molecule or ion to bond with the central metal and compound-complex) and the bivalent cations are effective factors in antibacterial properties of these NPs. The main purpose of this paper is to review the previous studies in order to determine the mechanism of antibacterial properties of these NPs and their influential factors due to the increasing use of these metal NPs in various fields.

Mild temperature photothermal assisted anti-bacterial and anti-inflammatory nanosystem for synergistic treatment of post-cataract surgery endophthalmitis

“…Multiple antibacterial mechanisms of nanomaterials were reported, such as damage to the bacterial membrane, DNA damage, RNA effluxes, oxidative stress, photothermal antibacterial, inhibition of energy metabolism, and so on 25 , 46 - 49 . Furthermore, the released Silver ion 50 and Copper ion 51 could also kill bacteria and the antibacterial activity of AuAg NPs was tested ( Figure S11 ). Besides, the release of ions was promoted by irradiation which could enhance the antibacterial effect.…”

Investigation of Nanoparticle Metallic Core Antibacterial Activity: Gold and Silver Nanoparticles against Escherichia coli and Staphylococcus aureus

“…Moreover, both their size and morphology were not altered when introduced into the bacterial culture medium. According to the literature, four to seven different mechanisms of action for MNPs as an antibacterial agent are described [ 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ]. For example, Lee and Jun described four main routes of antibacterial mechanism of AgNPs, namely (i) adhesion to the cell membrane, (ii) penetration onside the cell, (iii) ROS generation and cellular toxicity, and (iv) genotoxicity.…”

Antimicrobial Nanostructured Coatings: A Gas Phase Deposition and Magnetron Sputtering Perspective

“…The technological importance of NMs is due to their tunable physicochemical characteristics, such as optical absorption [6][7][8], electrical conductivity [9,10], photothermal characteristics [11], optical [12,13] and photoacoustic sensing [14,15], surface enhanced Raman scattering effects [16,17], chemical state [18], and bactericidal functionalities [19][20][21]. In particular, the latter research sector has been driven by the interest in understanding the interactions and effects of nanoparticles (NPs) on living organisms [20][21][22][23][24][25][26][27], with prominent attention towards the wet synthesis of NMs and NPs and the study of their effect on cells and bacteria in solution. More recently, the effort of the scientific community in developing NMs-based antimicrobial agents has been stimulated by the emergence of multi-drug-resistant pathogens, posing a world-wide challenge with a large socio-economic impact [28,29].…”