The Initiation of Respiration After Anaesthesia Accompanied by Passive Pulmonary Hyperventilation

Acid-Base Changes in Arterial Blood Associated With Spontaneous and Controlled Ventilation During Anaesthesia

“…In 9 of 17 neurosurgical patients studied, arterial Pco2 was lower on resuming spontaneous respiration after surgery than in the conscious state before anaesthesia, confirming that the initiation of natural respiration at the end of surgical operations depends on many factors other than arterial Pco2 (Cutter and King, 1961;Utting and Gray, 1962). It was interesting, also, that while the fall in standard bicarbonate which occurred consistently at this time was associated with rises in arterial Pc02, these were not necessarily to above the preanaesthetic level.…”

Methods of Elevation of Pco2 for Restoration of Spontaneous Breathing After Artificial Ventilation of Anaesthetized Patients

“…Depression of Pco 2 below the apnoeic threshold will almost invariably initiate or maintain respiratory arrest in an unconscious patient, although awake patients will often breathe in spite of severe respiratory alkalosis (Hanks, Ngai and Fink, 1961;Fink, 1961a). Breathing will also recommence in alkalotic patients who are only very lightly anaesthetized (Utting and Gray, 1962).…”