Incidencesregarding patient safety still occur,and not all are reported to the Hospital Patient Safety Committee. The aim studyto analyze the employee relationship influences the work unit staff's intention in implementingthe patient safety program-the study was conducted bythe quantitative design of observational analytics and through a cross-sectional staff approach. The research sites includedSidoarjo Regional Hospital, Anwar Medika Sidoarjo Hospital, and Ahmad Yani Surabaya Islamic Hospital. The research collects data during May-July 2019. The variables consist of employee relationship as the independent variable and intention as the dependent variable. The results show that the development stage's employee relationship was broadly establishing (46.51%), whereas, for the relationship stage, it was a majority of trusts (72.09%). The source intention stage was mostly personal intention(62.79%), and at the intention level, most of the distal intention was 84.88%. The leadership type affects theworking unit staff's discretionto implement patient safety programs in hospitals, with employee relationships as a variable mediator.The study concluded that the employee relationships had a significant influence on the working unit staff's intention in hospitals to carry out patient safety programs. However,employee relationships affect the work unit staff's intention to carry out the patient safety program.