2023
DOI: 10.3390/brainsci13071086
|View full text |Cite
|
Sign up to set email alerts
|

The Interaction of Glycemia with Anxiety and Depression Is Related to Altered Cerebellar and Cerebral Functional Correlations

Abstract: Depression, type 2 diabetes (T2D), and obesity are comorbid, and prevention and treatment of all three diseases are needed. We hypothesized an inverse relationship between the connectivity of the cingulo-opercular task control network with the somatosensory mouth network and the interaction between HbA1c and depression. Three-hundred and twenty-five participants (BMI: 26.11 ± 0.29; Achenbach adult self-report (ASR) DSM depressive problems T-score (depression): 54.60 ± 6.77; Age: 28.26 ± 3.90 y; adult self-repo… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

1
0
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
3

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
(1 citation statement)
references
References 60 publications
1
0
0
Order By: Relevance
“…Additionally, the PRS generated from EEfRT hard-task choice percentage was a significant predictor of self-reported levels of psychopathology in our adult participants; specifically, the PRS predicted elevated levels of symptomatology on scales that previous research has associated with anxiety, depressive disorders, and SCZ (Feng et al, 2018;Jackson & Bernard, 2022;Shearrer, 2023). These findings provide empirical support for the concept of a genetic basis for effort-based reward behavior that is associated with a wide variety of diagnostic forms or dimensions of psychopathology.…”
Section: Magma Gene-level and Gene-set Analysessupporting
confidence: 71%
“…Additionally, the PRS generated from EEfRT hard-task choice percentage was a significant predictor of self-reported levels of psychopathology in our adult participants; specifically, the PRS predicted elevated levels of symptomatology on scales that previous research has associated with anxiety, depressive disorders, and SCZ (Feng et al, 2018;Jackson & Bernard, 2022;Shearrer, 2023). These findings provide empirical support for the concept of a genetic basis for effort-based reward behavior that is associated with a wide variety of diagnostic forms or dimensions of psychopathology.…”
Section: Magma Gene-level and Gene-set Analysessupporting
confidence: 71%