The internal secretions of the ovary, by A. S. Parkes.

Parkes, A. S.

doi:10.5962/bhl.title.7046

Cited by 87 publications

(49 citation statements)

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“…Observations on the baboon, however, a species in which swelling is very prominent, showed that it represented a true oedema, and suggested that the swelling is due to transudation of fluid from the capillary bed into the intercellular spaces [Zuckerman, 1930]. Since it was known at the time that sexual-skin changes are due to oestrogenic action [Allen, 1927;Hartman, 1927;Zuckerman, 1930;Parkes & Zuckerman, 1931], it followed that oestrogen itself is responsible for water retention. This conclusion was established in a study of the water balance of a normal pig-tailed monkey, M. nemestrina [Krohn & Zuckerman, 1937], and of the rhesus monkey, M. mulatta, when injected with oestrogen [Fisher & Zuckerman, 1937].…”

mentioning

confidence: 96%

The Effect of Steroid Hormones on the Water Content of Tissues

Zuckerman¹,

Palmer²,

Hanson³

1950

Journal of Endocrinology

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mentioning

confidence: 96%

The Effect of Steroid Hormones on the Water Content of Tissues

Zuckerman¹,

Palmer²,

Hanson³

1950

Journal of Endocrinology

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“…It is noteworthy that testis grafts of the saline frozen series also persisted, unlike similarly treated ovary grafts [Parkes & Smith, 1953]. These testis grafts, some of which showed androgenic function 141 days after implantation, were on the whole poorly vascularized and showed little capacity for growth.…”

Section: Scrotal Graftsmentioning

confidence: 91%

“…Grafts placed in the scrotum consisted of one testis cut in four pieces in each host. In earher experiments, Parkes & Smith [1953] had shown that rat ovarian tissue would revive and grow after slow freezing if first soaked in glycerol-saline (1-5 ml. glycerol added to 8-5 ml.…”

Section: Methodsmentioning

confidence: 99%

Spermatogenesis and Endocrine Activity in Grafts of Frozen and Thawed Rat Testis

Deanesly¹

1954

Journal of Endocrinology

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Testes of prepubertal rats retain their capacity to grow and differentiate as homografts after gradual freezing to \m=-\79\s=deg\C and thawing. Spermatozoa are formed in scrotal grafts.Early work on testis homografting has been reviewed by Turner [1938] and Moore [1939, 1951]. It has been shown by these workers, and others, that functional testis grafts can be made in the rat and other mammals. In 1924 Moore reported active mitosis in the germinal epithelium of guinea-pig testis grafts, but up to that time he believed that no one had found spermatozoa in a mammalian testis graft, apart from one instance recorded in this paper where an immature testis was grafted into the scrotal sac of a castrated 60-day rat and examined after 6 months. Later, Moore reported further cases of spermatozoa in grafts but only in scrotal grafts where the temperature is lower. Some workers have attributed absence of full spermato¬ genesis to absence of excurrent ducts, but Moore's findings do not support this [Moore, 1939].Other experiments on the transplantation of immature testes into adult rats with varying results include those of Richter & Wislocki [1928], Lipschiitz & Ibieta [1932], Pfeiffer [1935] and Browman [1937]. Turner [1938] described a comprehensive series of homotransplants of prepuberal testes into normal and castrate male and female rats. He experimented with different body sites but obtained his best grafts from within the anterior chamber of the eye. Some of the grafts contained sperm heads 38 days after transplantation. In general the graft interstitial tissue was well developed and maintained seminal vesicle and prostate secretion in castrate hosts. The full spermatogenesis, where found, is attributed to early vascularization of the grafts and to the lower temperature of the eye chamber, approximating to that of the scrotum, and 4-6°C below that of other body sites. Williams [1950] studied living testis grafts in the eye chamber of rabbits with special reference to the behaviour of the different testis constituent cells.

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“…Proper functioning of the accessory sex glands in males has been shown to be influenced by the adenohypophysial and gonadal hormones (Burrows, 1949;Parkes, 1966;Turner, 1966). Neumann, Van Berswordt-Wallrabe, Elger, Steinbeck, Hahn & Kramer (1970) reported that an antiandrogen, cyproterone acetate (CA), caused a marked atrophy of the accessory sex glands and suppres¬ sion of spermatogenesis.…”

mentioning

confidence: 97%