The Interval of Development of Testicular Carcinoma in a Patient With Previously Demonstrated Testicular Microlithiasis

Golash, Anurag; Parker, Joanne E.; ENNIS, OWAIN; Jenkins, B. J.

doi:10.1097/00005392-200001000-00062

Cited by 7 publications

(9 citation statements)

References 3 publications

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“…Given the added evidence regarding the association of CIS with TM in small testes and infertile testes, it may be that there is some underlying process that causes [34][35][36][37][38]. Only prospective studies can demonstrate whether patients with pre-existing TM are at increased risk of future tumour, and could benefit from follow-up to diagnose future tumours early.…”

Section: Discussionmentioning

confidence: 99%

Testicular calcification and microlithiasis: association with primary intra-testicular malignancy in 3,477 patients

et al. 2006

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The prevalence of all forms of scrotal and testicular calcification and their association with testicular tumour in a symptomatic paediatric and adult population was investigated. A retrospective study of all testicular ultrasound examinations performed at a single centre over a 5-year period was undertaken. All studies were performed by experienced operators, recorded in a standard method, using high-frequency linear array transducers (> or =10 MHz). All available images (95.2%) were reviewed by experienced operators, recording the location and type of scrotal and testicular calcification according to a pre-determined schedule. A total of 3,854 studies were reviewed on 3,477 patients (age range: 1 month to 91 years). In the adult group, 3,279 examinations were analysed. Prevalence of testicular microlithiasis (TM) was 2.0%, and the prevalence of other non-microlithiasis testicular calcification (non-TM calcification) was 1.7%. Testicular tumour was associated with TM (odds ratio 9.5, P<0.001) and non-TM calcification (odds ratio 11.4, P<0.001) but not with other types of scrotal calcification. A total of 198 paediatric examinations were analysed. Prevalence of TM was 2.0% and the prevalence of non-TM calcification was 0.5%. One tumour (lymphoma) was identified, with no associated calcification. This study confirms the reported association between TM and testicular tumour and finds a previously unreported association between non-TM calcification and testicular tumour.

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Section: Discussionmentioning

confidence: 99%

Testicular calcification and microlithiasis: association with primary intra-testicular malignancy in 3,477 patients

et al. 2006

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“…La microlithiase est une entité anatomique particulière, qui correspond à de multiples dépôts calciques à l'intérieur des tubes séminifères testiculaires, uni-ou bilatérale [7][8][9]. On ne connaît pas la pathogénie de ces dépôts calciques.…”

Section: Microlithiaseunclassified

“…Au-delà de 20 microcalcifications, une surveillance échographique tous les deux ans est nécessaire [9], en raison de l'association possible avec une tumeur maligne [7][8][9].…”

Section: Microlithiaseunclassified

“…On connaît l'association des séminomes avec des microcalcifications intratumorales [7,9], mais également avec des microcalcifications dans le tissu testiculaire sain (Fig. 12).…”

Section: Microlithiaseunclassified

“…Nous avons vu également se développer un séminome sur une microlithiase connue, au bout de plusieurs années de surveillance [9].…”

Section: Microlithiaseunclassified

See 2 more Smart Citations

Apport de l’échographie dans le bilan d’une infécondité masculine

Granier

2009

Basic Clin. Androl.

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Testicular Microlithiasis, Long Term Experience of a Single Institution

Kimuli

Beckley

Cast

et al. 2011

British Journal of Medical and Surgical Urology

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Introduction: Several studies have reported an association between testicular microlithiasis (TML) and testicular malignancy with some suggesting the concordance to be as high as 40%. In 2000, we published a large study of 4819 patients referred for scrotal ultrasound (USS) at four referral centers. Based on our findings we recommended ultrasound surveillance of patients with TML. The aim of this study was to determine the long-term outcome of our surveillance regimen. Methods: We reviewed the prospective database of all men diagnosed with TML at USS between 1996 and 2006 at our institution. All patients diagnosed with TML were scheduled for six-monthly USS and in addition they were given instructions to perform regular self-examination. Fifteen years after the surveillance program was commenced, all patients were contacted and asked to complete a short questionnaire. Results: 57 men were diagnosed with TML with no concurrent or previous testicular tumour. The mean period of follow up was 28.4 months (3–102). Only one man developed testicular cancer during the follow up period. Conclusions: We currently recommend regular testicular self-examination of all men with TML and reserve USS surveillance for selected patients with associated risk factors for testicular malignancy.

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The Interval of Development of Testicular Carcinoma in a Patient With Previously Demonstrated Testicular Microlithiasis

Cited by 7 publications

References 3 publications

Testicular calcification and microlithiasis: association with primary intra-testicular malignancy in 3,477 patients

Testicular calcification and microlithiasis: association with primary intra-testicular malignancy in 3,477 patients

Apport de l’échographie dans le bilan d’une infécondité masculine

Testicular Microlithiasis, Long Term Experience of a Single Institution

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