2016
DOI: 10.4103/0301-4738.190137
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The investigation on the role of mitochondrial fusion protein 1 in the development of myopia

Abstract: Purpose:The aim of this study is to preliminarily investigate the expression of mitochondrial fusion protein 1 (MFN1) in a lens-induced animal myopia (LIM) model and to explore the relationship between MFN1 and the visual development.Materials and Methods:MFN1 gene expression in guinea pigs was examined during the development of minus LIM, 15 tri-colored guinea pigs were obtained, and one eye of each pig was randomly selected and treated with −7.00D lenses. Ocular refraction and axial length were collected bef… Show more

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