2019
DOI: 10.1002/jsde.12297
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The Investigations of Construction and in vitro Release of Curcumin Lyotropic Liquid Crystals: Phase Diagrams, Small Angle X‐ray Scattering, Rheological Technology, and Release Kinetics

Abstract: In this study, hexagonal and cubic lyotropic liquid crystals (LLC) were constructed in Brij 97‐Tween 40 (MS82, MS64 and MS46)/OLA/H2O systems to encapsulate curcumin. MS82, MS64, and MS46 indicated that the mass ratio of Brij 97/Tween 40 was 8/2, 6/4, and 4/6. The microstructure of curcumin LLC was studied using small angle X‐ray scattering (SAXS). Phase diagrams showed that the increase of MS reduced the phase transition temperature (TC). Particularly, the TC of sample C1Cur [Brij 97‐Tween 40 (MS46)/OLA/H2O =… Show more

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