Aims: The popularity of CBT as a first-line treatment for many psychological disorders has resulted in its application to ethnically diverse populations, despite its evidence base being rooted in Western populations. Equivalence in results between clients from Middle-Eastern and Western ethnicity has not been established. The aims of this review were to summarise the literature on CBT for mental health difficulties among Arab individuals in Middle Eastern countries and Arab minority individuals in Western countries. Method: Studies were identified through a systematic literature search using the databases PsycINFO, Web of Science, and PUBMED. Results: Eight studies were included in this review, encompassing quantitative, qualitative, and case-report articles. All studies reported on the outcome of CBT interventions with Arab participant(s). Conclusion: Despite the scarcity of studies, small sample sizes, and a majority of non-clinical samples, the outcomes demonstrated that Arab individuals benefited from CBT. In studies that compared Western and Arab samples, the results were better for Western samples, indicating that CBT is less efficacious with Arab clients. A discussion on the strengths and limitations of the studies is presented. Author (Year) Location Mental health difficulty in focus Design, Primary Outcome Measures Sample characteristics Key Findings Effect size where available Kayrouz et al. (2015) Australia Anxiety and Depression Quasi-experimental design. Patient Health Questionnaire-9-item (PHQ-9; Kroenke et al., 2001) and Generalised Anxiety Disorder-7-item scale (GAD-7; Spitzer et al., 2006). Introduction: The majority of the psychological understanding of anxiety and CBT treatment for anxiety disorders has been derived from research that has been undertaken with European and North American populations. Aim: This study aimed to improve our understanding of the experiences of anxiety and panic related cognitions among Saudi-Arabian individuals and to examine the potential role that culture might have in influencing their symptom expression. Methods: Given the lack of previous research, this study adopted an exploratory, qualitative approach using Thematic Analysis. Semi-structured interviews were undertaken with 14 participants with an ICD diagnosis of panic and anxiety from Saudi Arabia. Results: The results demonstrated that Saudi-Arabian participants misinterpret their symptoms in the way predicted by CBT. Differences in panic cognitions were related to the Saudi-Arabian sample's emphasis on negative social evaluation, and two previously unidentified cognitions: separation and loss from loved ones, and Jinn possession. Conclusion: The results suggests that CBT for anxiety can be applied to Saudi-Arabian clients without systematic modification.