The juice of fresh leaves of Boerhaavia diffusa L. (Nyctaginaceae) markedly reduces pain in mice

Hiruma-Lima, Clélia Akiko; Gracioso, J.S.; Bighetti, E.J.B.; Robineou, L. Germonsén; Brito, Alba Regina Monteiro Souza

doi:10.1016/s0378-8741(00)00178-1

Cited by 110 publications

(61 citation statements)

References 17 publications

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“…The main chemical ingredients of this plant include alkaloids (punarnavine), rotenoids (boeravinones A to J) and flavones [20] .…”

Section: Contents Lists Available At Sciencedirectmentioning

confidence: 99%

“…A stock solution of DPPH (400 毺g/mL) (Sigma-Aldrich, USA) was prepared in methanol, which gave initial absorbance of 0.197, and 100 毺L of this stock solution was added to 5 mL of solutions of B. diffusa extracts of different concentrations (20-100 毺g/mL). The solutions were then mixed properly and kept in dark for 20 minutes and the absorbances weremeasured at 517 nm. Scavenging activity was expressed as the percentage inhibition calculated using the following formula:…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

See 1 more Smart Citation

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Apu

Liza

Jamaluddin

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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“…The main chemical ingredients of this plant include alkaloids (punarnavine), rotenoids (boeravinones A to J) and flavones [20] .…”

Section: Contents Lists Available At Sciencedirectmentioning

confidence: 99%

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Apu

Liza

Jamaluddin

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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“…Traditionally in Ayurveda it has been used for the cardiac disorders. 11,12 It has been reported to have analgesic and anti-inflammatory, 13 antistress, 14 antioxidant, 15 hepatoprotective, 16 anticonvulsant 17 and diuretic. 18 Earlier we reported that ethanolic extract of whole plant of Boerhaavia diffusa had protected cardiotoxicity induced by doxorubicin.…”

Section: Introductionmentioning

confidence: 99%

Effect of Ethanolic Extract Fractions of Boerhaavia diffusa in Doxorubicin-induced Myocardial Toxicity in Albino Rats

Nimbal¹,

Koti²

2017

JYP

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“…This plant is commonly known as red hogweed, tar vine, red spiderling, wineflower. Roots and leaves of this plant are used by many tribes in India for their anti-diabetic 3 , analgesic 4 , diuretic 5 , immunomodulatory 6,7,8 , anti-oxidant 9 , hepatoprotective 10 and anti-lymphoproliferative 11 properties. The root of B.diffusa contains alkaloids (punarnavine), rotenoids (boeravinones A-O), aminoacids, flavonoids, esacosanoic, stearic, β-sitosterols, tetracosanoic and ursolic acids 9,12 .…”

Section: Introductionmentioning

confidence: 99%

“…Pharmacological potential of B.diffusa were widely studied in boeravinones. Boeravinone E binds the GM-CSF and TNF-α receptors stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including dendritic cells, granulocytes, macrophages, eosinophils and erythrocytes 4 .…”

Section: Introductionmentioning

confidence: 99%

Isolation, Purification and Characterization of Boeravinone B From Boerhaavia Diffusa Linn.

Krishnamoorthy¹,

Muthukumaran²,

Maheswaran³

et al. 2017

Int. Res. J. Pharm.

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Boerhavia diffusa is a medicinal plant used in treatment of autoimmune diseases, cancers and inflammation. In the present study, methanolic extraction of roots of Boerhaavia diffusa was carried out and presence of Boeravinone B was identified from Thin Layer Chromatography and reverse phase HPLC. The methanolic root extract was run in TLC containing the mobile phase as toluene: ethyl acetate: methanol in the ratio (7:1:2). Retention factor for Boeravinone B in B.diffusa extract was found to be 0.461. RP-HPLC was carried out from the mobile phase consisting of acetonitrile and water at the ratio of 50:50 at 35 °C with a flow rate of 1.0 mL/min in C18 reverse phase column. Retention time of Boeravinone B was found to be 13.8 min. Linearity range of the concentration of extracted Boeravinone B was 5 -120 μg/ml and the correlation coefficient (R 2 ) value was found to be 0.997±0.003. Recovery was found to be 90.6% -92.8%. The limit of detection (LOD) of Boeravinone B was found to be 2 μg/ml and limit of quantitation (LOQ) was found to be 5 μg/ml. Presence of functional groups such as phenyl groups at 1450.47 cm -1 , 1591.27 cm -1 , C=C (Carbon skeleton) at 1618.28 cm -1 and Isoflavonoid structure at 1649.14 cm -1 of absorption spectra of isolated Boeravinone B were characterized by FTIR spectroscopy through recording absorption spectra. Thus, a rapid, economical and viable method was developed for isolation, purification and characterization of Boeravinone B.

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The juice of fresh leaves of Boerhaavia diffusa L. (Nyctaginaceae) markedly reduces pain in mice

Cited by 110 publications

References 17 publications

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Effect of Ethanolic Extract Fractions of Boerhaavia diffusa in Doxorubicin-induced Myocardial Toxicity in Albino Rats

Isolation, Purification and Characterization of Boeravinone B From Boerhaavia Diffusa Linn.

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