“…The most salient features desired for bioactive glasses as listed above can be obtained while totally excluding the alkalis and by a rational combination of all the remaining pertinent glass components, as has been plenteously demonstrated by Ferreira et al in several works published since 2011 [77,135,151,275,277,279,280,281,282,283,284,285,298,299,300,303,304,305,306,307,308,309,310,311,312,313]. Following a completely different concept, the alkali-free bioactive glass compositions were based upon the compositions of minerals that are biocompatible and bioactive, such as diopside, fluorapatite, wollastonite, and tricalcium phosphate, in different combinations and proportions.…”