The kinetics of adsorption of tetracycline on chitosan particles

Abstract

Experiments to monitor and characterize the kinetics of adsorption of tetracycline on chitosan particles are reported in this work. The same pseudo-order kinetics that has been widely used for describing the adsorption in systems related to wastewater purification and drug loading was used to treat the present data. As some unexpected results came out from the experiments, it was necessary a detailed deduction for this sort of kinetics to be carried out, so that approximations related to short and long times were obtained. Firstly it was shown that an apparently linear t/q(t) versus t relationship did not imply a pseudo-second-order sorption kinetics, differently of what has been repeatedly reported in the literature. It was found that this misinterpretation could be avoided by using non-linear regression. Finally, the adsorption of tetracycline on chitosan particles was analyzed, using the insights obtained from theoretical analysis, and the parameters generated were used to analyze to adsorption kinetics and to propose an adsorption mechanism.

A Review on the Adsorption Studies of Tetracycline onto Various Types of Adsorbents

“…Sorbo and Merck commercial grade activated carbon(carbon S and carbon M) (Caroni et al, 2009) was used. MnFe 2 O 4/ activated carbon (Shao et al ., 2012 based composite was used in the adsorption studies of TET and column studies were carried out onto coal and coconut based granular activated carbon (Choi et al,2008).…”

“…Controlled drug release polymeric devices have been a unique interest in the drug development zone as they hit the specific target with the active compound and also provide a good control on the rate of dosage release. Several different types of polymer have been used among which chitosan (Caroni et al, 2009) (Caroni et al, 2012) takes a special note from environmental, safety and cost point of view. In this study, chitosan was first purified by dissolving the crude chitosan in 2% acetic acid solution, and the resultant solution was filtered in two stages using a nylon screen filter, precipitated using 5% NAOH solution, finally the powder was separated by filtration and washed with distilled water and purified.…”

“…In case of cryogel (Bagda et al, 2013) According to the intra particle diffusion model (Shi et al, 2011), the adsorption of TET on nitrifying granules was found to be controlled by both surface and intra particle diffusion process. In case of chitosan (Caroni et al, 2009) (Caroni et al, 2012) …”

Synthesis of low molecular weight alginic acid nanoparticles through persulfate treatment as effective drug delivery system to manage drug resistant bacteria

“…The supernatant was centrifuged at 14,000 rpm for 30 min and then filtered through a 0.22 µm membrane filter. Free tetracycline in the supernatant suspension was the amount of drug not encapsulated into LMWA nanoparticles; its concentration was assayed by spectrophotometry at 423 nm [25]. The PLE % was calculated from equation (2):…”

Kinetics Modeling and Mechanism of Organic Matter Absorption in Functional Fiber Based on Butyl Methacrylate-Hydroxyethyl Methacrylate Copolymer and Low Density Polyethylene

“…An important aspect in the study of absorption is the kinetics that describes the effect of time on the interactions between absorbate and absorbent [28] . It is well known that first-order and second-order kinetic expressions are the most commonly used kinetics models in the literature [29][30][31][32][33][34][35] , so the first-order and second-order kinetic expressions were selected to correlate experimental data with theoretical data for organic matter absorption at the solid=liquid interfaces in this work.…”