The Kinmen Neurological Disorders Survey (KINDS): A Study of a Chinese Population

Liu, Hsiu Chih; Wang, Shuu Jiun; Fuh, Jong Ling; Liu, Chia Yia; Lin, Kong Ping; Lin, Cheng; Wang, Pei Ning; Lin, Ker Neng; Wang, Hsiao Chien; Chen, Hsi Ming; Chang, Ray Hsienho; Larson, Eric B.; Wu, Gin Son; Chou, Pesus; Teng, Evelyn L.

doi:10.1159/000109672

Cited by 30 publications

(25 citation statements)

References 13 publications

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“…ET is a worldwide condition with a high prevalence [6,7,8,9,10,11,12]. The disorder also has a relatively restricted phenotype in the sense that the number of clinical features is relatively small.…”

Section: Resultsmentioning

confidence: 99%

‘Essential Tremor' or ‘the Essential Tremors': Is This One Disease or a Family of Diseases?

Louis¹

2013

Neuroepidemiology

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There is accumulating evidence that the entity referred to as ‘essential tremor' (ET) is not a single disease. It may be a family of diseases better referred to as ‘the ETs'. This review will summarize the following evidence: (1) the presence of etiological heterogeneity; (2) the heterogeneity of findings in postmortem studies, thus suggesting several diseases; (3) the recent discussion that age of onset may be an important marker of disease heterogeneity; (4) the clinical expansion of the concept of ET in recent years to include a broader range of tremor phenomenology, other motor features (gait ataxia), other involuntary movements (dystonia), and nonmotor features (cognitive problems, psychiatric problems), some of which could be primary; (5) the heterogeneity of pharmacological response profiles and clinical progression, and (6) the association of ET with Parkinson's disease, Alzheimer's disease, and possibly progressive supranuclear palsy, with the possibility that some ET patients are more predisposed to develop one of these.

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Section: Resultsmentioning

confidence: 99%

‘Essential Tremor' or ‘the Essential Tremors': Is This One Disease or a Family of Diseases?

Louis¹

2013

Neuroepidemiology

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“…According to the previous epidemiological studies in Taiwan (1987Taiwan ( to 1996, the prevalence of dementia in community elders was between 1.7 and 4.4%, and the most common cause of dementia was Alzheimer's disease, followed by vascular dementia [11][12][13][14] . The prevalence of dementia in the long-term care units of Taiwan was at least 10 times higher than what we would expect considering the community studies.…”

Section: Discussionmentioning

confidence: 99%

“…Accordingly, Taiwan is facing a rapid increase in the demand for long-term care facilities. Previous community-based research shows that the prevalence of dementia in different areas of Taiwan was from 1.7 to 4.4% [11][12][13][14] . However, there has been no such survey on the cognitive status of the elder residents in the long-term care facilities of Taiwan.…”

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confidence: 99%

Institution Type-Dependent High Prevalence of Dementia in Long-Term Care Units

et al. 2007

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Background/Aims: It is estimated that there are 90,000 patients with dementia in the 23 million habitants of Taiwan, with a few institutions specialized in dementia care. To assess the need of institutional care for dementia, we investigated the institution prevalence of dementia. Methods: We performed stratified randomized sampling of elder residents from different types of institutions in different regions of Taiwan. A 2-stage survey with screening and clinical confirmation was carried out in 2004. Results: In total, 1,525 residents aged 65 years and over in 60 institutions participated in the study in which 1,308 elders completed the 2-stage survey. Among these, 631 elders were diagnosed as having dementia. The dementia prevalence was 26.8% in the residential houses, 61.8% in the assisted living facilities and 64.5% in the nursing homes. Vascular dementia was the leading cause of dementia in the institutions. Old age, diabetes mellitus and family history of dementia increased risks for both Alzheimer’s disease and vascular dementia. Conclusion: The investigation showed that the prevalence of dementia in the long-term care units of Taiwan was much higher than those from community studies and the high prevalence in the institutions depended on the type of the long-term care unit.

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“…Subjects were recruited from two sources, namely (1) participants in the Kinmen Neurological Disorders Survey, a community-based study [29], and (2) patients who visited the Memory Clinic of the Neurological Institute of the Taipei Veterans General Hospital (Taipei VGH). Because the subjects from the Kinmen Neurological Disorders Survey were mostly illiterate, their mean CASI C-2.0 score was lower than the mean score of the subjects from Taipei VGH.…”

Section: Subjectsmentioning

confidence: 99%

Cutoff Scores of the Cognitive Abilities Screening Instrument, Chinese Version in Screening of Dementia

Lin

Wang

Liu

et al. 2002

Dement Geriatr Cogn Disord

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135

133

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The purpose of this study of dementia screening was to obtain different cutoff scores of the Cognitive Abilities Screening Instrument, Chinese versions (CASI C-2.0) for subjects with different educational backgrounds. The diagnosis of dementia was based on the Diagnostic and Statistical Manual of Mental Disorders, ed 3 revised or ed 4 criteria. To diagnose Alzheimer’s disease, the guidelines of the National Institute of Neurological and Communicative Disorders and Stroke and Alzheimer’s Disease and Related Disorders Association was followed. The severity of dementia was determined on the Clinical Dementia Rating scale. Altogether 2,096 subjects, aged 65 years and more, were included. Of them, 1,178 were normal and 918 were demented. Their performance on CASI C-2.0 was influenced by their education and age. Gender difference on CASI C-2.0 scores was only significant in the illiterate, but not in the literate group. We recommend that the population be divided into three levels, namely those who (1) had no formal education (Edu = 0); (2) received 1–5 years of schooling (Edu = 1–5), and (3) received 6 or more years of education (Edu ≧6). The cutoff scores of CASI C-2.0 in the diagnosis of dementia in these three educational groups were as follows: Edu = 0: 49/50 (sensitivity = 0.83; specificity = 0.85); Edu = 1–5: 67/68 (sensitivity = 0.83; specificity = 0.91), and Edu ≧6: 79/80 (sensitivity = 0.89; specificity = 0.90).

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The Kinmen Neurological Disorders Survey (KINDS): A Study of a Chinese Population

Cited by 30 publications

References 13 publications

‘Essential Tremor' or ‘the Essential Tremors': Is This One Disease or a Family of Diseases?

‘Essential Tremor' or ‘the Essential Tremors': Is This One Disease or a Family of Diseases?

Institution Type-Dependent High Prevalence of Dementia in Long-Term Care Units

Cutoff Scores of the Cognitive Abilities Screening Instrument, Chinese Version in Screening of Dementia

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