Technology transformation and transhumanism are closely related concepts that revolve around the idea of using advanced technologies to fundamentally change and enhance human capabilities. The study uses ADO model is applied to determine the impact of digital transformation on human resourcest. The major output or the contribution of the study is to:(i) to provide a complete review of technology transformation in businesses in context to impact on the human resource (ii) identifying the major antecedents that can become opportunity/challenge for the human resource, (iii) offering a connection between business technology transformation in other aspects of the economies like management, business economics, marketing etc. In addition, the findings of the study reflect the positive and negative impact of technology transformation on the human resources. This approach can be valuable in providing a strong foundation for further research, policy making and decision-making for enhancing the status of human resource dynamics and technology transformation.