The Lack of Effect of a Prophylactic Dose of Enoxaparin on Thrombin Generation in Patients Subjected to Nephrectomy Because of Kidney Cancer

Pneumonectomy due to lung cancer results in a more pronounced activation of coagulation system than lobectomy

“…Similar observation was made in patients undergoing nephrectomies due to renal cancer, where concentration of TAT complexes was also elevated on the seventh postoperative day [11]. The fact that TF and E-selectin were within normal levels can be explained by the influence of LMWH, which is administered in these patients as a thrombo-embolic prophylaxis.…”

“…Patients undergoing thoracotomy due to malignant diseases are recommended to receive a combined regimen of pharmacologic and mechanical thromboprophylaxis [5][6][7][8][9][10][11]. According to recent recommendations, thromboprophylaxis with low-molecular-weight heparin (LMWH) should be administered preoperatively and for at least 7-10 days postoperatively [5,11,12].…”

“…According to recent recommendations, thromboprophylaxis with low-molecular-weight heparin (LMWH) should be administered preoperatively and for at least 7-10 days postoperatively [5,11,12].…”