The Larvacidal Activity of Moringa aloifera Extract Leaf to The Larva’s Aedes aegypti Mortality

Yasi, Ratna Mustika; Harsanti, Restiani Sih

doi:10.19184/ams.v4i3.8710

Cited by 5 publications

(6 citation statements)

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“…These results were not aligned with the previous research, which revealed that the M. oleifera leaf ethanol extract contained saponins as its secondary metabolite compound. 7,10,12 The absence of saponins in this research could have occurred due to several factors that affected the extraction process. Factors influencing the maceration process results are temperature, solvent types and concentration, duration, and other factors.…”

Section: Discussionmentioning

confidence: 95%

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Moringa oleifera Leaf Ethanol Extract Inhibits Toxoplasma gondii Tachyzoites Replication

Wihanto

Waworuntu

Tedyanto

et al. 2023

IJTID

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The various infection routes of Toxoplasma gondii that are close to daily life strongly support the incidence of toxoplasmosis. The emergence of drug-resistant Toxoplasma gondii strains raises future concerns. Moringa leaf ethanol extract has been shown to have several anti-pathogen activities, which could have an anti-Toxoplasma effect. This research was conducted to analyze the anti-Toxoplasma effect of moringa leaf ethanol extract against tachyzoites replication in Toxoplasma gondii and the correlation between extract doses with the number of tachyzoites. Mice were divided into five groups. The negative control group (Group I) received CMC-Na solution. The positive control group (Group II) received spiramycin 100 mg/kg BW. The treatment groups received moringa leaf ethanol extract 250 mg/kg BW (group III), 500 mg/kg BW (group IV), and 1000 mg/kg BW (group V), respectively. Mice were injected with 1 x 105 tachyzoites/0.1 mL/mice intraperitoneally on the first day. Moringa leaf ethanol extract and spiramycin were given orally once daily for three days. The number of tachyzoites in the intraperitoneal fluid was calculated on the fifth day. The results have shown that there were significantly lower differences (P < 0.05) in group IV (P = 0.021) and group V (P = 0.022) compared to group I. There was also a significant negative correlation between the extract doses and the number of tachyzoites (P = 0.000; r = -0.781). Moringa oleifera leaf ethanol extract has an anti-Toxoplasma effect by inhibiting the tachyzoite replication at 500 mg/kg BW and 1000 mg/kg BW.

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Section: Discussionmentioning

confidence: 95%

“…[7][8][9] It also acts as a larvicidal. 10 A phytochemical analysis of M. oleifera leaf ethanol extract revealed alkaloids, phenolics, flavonoids, tannins, saponins, and terpenes as their bioactive compounds. 8,[11][12][13] It has rutin as its major flavonoid, gallic acid as its major phenolic acid, and lutein as its major carotenoid.…”

Section: Introductionmentioning

confidence: 99%

Moringa oleifera Leaf Ethanol Extract Inhibits Toxoplasma gondii Tachyzoites Replication

Wihanto

Waworuntu

Tedyanto

et al. 2023

IJTID

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“…Salah satu jenis alkaloid yang memiliki peran sebagai repellent adalah quinine. Alkaloid memiliki kemampuan sebagai racun perut, sehingga nyamuk menolak adanya pemberian ekstrak yang dioleskan pada lengan probandus (Yasi & Harsanti, 2018). Senyawa saponin berpotensi menghambat perkembangan nyamuk, karena memiliki efek toksik jika terhirup.…”

Section: Hasil Skrining Fitokimia Ekstrak Etanol Daun Paitanunclassified

Karakterisasi dan Potensi Ekstrak Daun Paitan (Tithonia diversifolia) sebagai Penolak Nyamuk Aedes aegypti

Wahyuni,

Swandono,

Mawardika

et al. 2023

Bioscientist j. ilm. bosbiol.

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The paitan plant (Tithonia diversifolia) contains alkaloids, saponins, flavonoids, tannins and phenolics which have the potential to prevent Dengue Hemorrhagic Fever (DHF). This plant also has various insecticidal activities. In society, there are many mentions of the paitan plant, so people need to know the characteristics of this paitan plant. The aim of this research is to determine the morphological characterization and specific fragments of the paitan plant, as well as to determine the activity and effective concentration of the ethanol extract of paitan leaves as a repellent for the Aedes aegypti mosquito. Two types of methods were used, namely descriptive qualitative for observing morphology, specific fragments, pollen, and phytochemical screening, and experimental methods for mosquito repellent testing, and calculating the protective power of the ethanol extract of paitan leaves. The results obtained are flowers consisting of two shapes, namely ribbon flowers in the outer circle, infertile, and tube shapes in the inner circle. Stomata are anomocytic type, while trichomes are non-glandular multicellular type. Pollen characteristics, namely small size, colpate, number 3, aperture shaped trizonocolpate with echinate ornamentation. The screening results for the ethanol extract of paitan leaves were positive for containing metabolite compounds, such as flavonoids, alkaloids, tannins, saponins, terpenoids and phenolics. The results of the mosquito repellent test showed that the higher the concentration of the extract, the fewer mosquitoes that landed. Calculation of protective power shows that the most effective concentration in repelling mosquitoes is 15%, namely 93.64%. The conclusion is that paitan (Tithonia diversifolia) leaf extract has potential activity as a repellent against Aedes aegypti mosquitoes with the most effective concentration being 15%.

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“…Sedangkan tanin dapat menurunkan intensitas makan yang berakibat terganggunya pertumbuhan serangga. Semakin tinggi konsentrasi larutan ekstrak kulit buah limus semakin banyak menyebabkan kematian larva (Yasi & Harsanti, 2018).…”

Section: Uji Skrining Fitokimiaunclassified

Formulasi dan Aktivitas Lotion Antinyamuk Aedes Aegypti dari Ekstrak Kulit Buah Limus (Mangifera Foetida Lour)

Nurmay Stiani,

Nurhayati,

Effendi

et al. 2022

jikd

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The purpose of this study was to determine the limus extract skin lotion (Mangifera foetida Lour) has activity against mosquitoes against Aedes aegypti mosquitoes. This research includes making simplicia, limus fruit extract, phytochemical screening; lotion extract formulation; physical lotion preparation evaluation; and testing of repellent activity in lotio preparations. The concentrations of the extracts tested for their activity as mosquito repellents were 5% and 10% w/v. The results showed that the rind extract of limus (Mangifera foetida Lour) could be formulated into mosquito repellent lotion at concentrations of 5 and 10% which had an evaluation of preparations that met the requirements, namely organoleptic, homogeneity, dispersibility and pH. Lotion of limus peel extract (Mangifera foetida Lour) at concentrations of 5 and 10% has activity against mosquitoes against Aedes aegypti mosquitoes with protection power reaching 100% at 2 hours for lotion with a concentration of 5% and lotion with a concentration of 10% providing more than 90% protectionie at 0, 2 to 3 hours in each replication with an average protection power of 100%. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas anti nyamuk dari lotion ekstrak kulit buah limus (Mangifera foetida Lour) terhadap nyamuk Aedes aegypti. Penelitian ini meliputi pembuatan simplisia, ekstrak kulit buah limus, skrining fitokimia; formulasi lotion ekstrak; evaluasi sediaan lotion dari segi fisik; serta pengujian aktivitas antinyamuk dalam sediaan lotion. Konsentrasi ekstrak yang diuji aktivitasnya sebagai antinyamuk adalah 5% dan 10% b/v. Hasil penelitian menunjukkan bahwa ekstrak kulit buah limus (Mangifera foetida Lour) dapat diformulasi menjadi lotion antinyamuk pada konsentrasi 5 dan 10% yang memiliki evaluasi sediaan yang memenuhi persyaratan yaitu organoleptik, homogenitas, daya sebar dan pH. Lotion ekstrak kulit buah limus (Mangifera foetida Lour) pada konsentrasi 5 dan 10% memiliki aktivitas antinyamuk terhadap nyamuk Aedes aegypti dengan daya proteksi mencapai 100% pada jam ke-2 untuk lotion konsentrasi 5% dan lotion konsentrasi 10% memberikan proteksi lebih dari 90% yaitu pada jam ke-0, 2 sampai jam ke-3 di setiap replikasi dengan rerata daya proteksi yaitu 100%.

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The Larvacidal Activity of Moringa aloifera Extract Leaf to The Larva’s Aedes aegypti Mortality

Cited by 5 publications

References 0 publications

Moringa oleifera Leaf Ethanol Extract Inhibits Toxoplasma gondii Tachyzoites Replication

Moringa oleifera Leaf Ethanol Extract Inhibits Toxoplasma gondii Tachyzoites Replication

Karakterisasi dan Potensi Ekstrak Daun Paitan (Tithonia diversifolia) sebagai Penolak Nyamuk Aedes aegypti

Formulasi dan Aktivitas Lotion Antinyamuk Aedes Aegypti dari Ekstrak Kulit Buah Limus (Mangifera Foetida Lour)

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