The length summation properties of layer VI cells in the visual cortex and hypercomplex cell end zone inhibition

Abstract

Layer VI of the visual cortex has been considered to be dominated by cells with very long receptive fields, typically summing to 8 degrees or more. We have re-examined this issue in a series of experiments in which the length tuning profiles of layer VI cells in the cat visual cortex have been quantitatively determined. Responses were assessed to optimally oriented bars of light of varying length drifted over the receptive field. The lengths were varied on a randomised interleaved sequence. Although our data confirm the presence of long field cells in layer VI, only 24% of a population of 119 cells had fields greater than 6 degrees in length. Fields greater than 8 degrees were only seen in 17% of cells. 61% of the population of cells had fields showing summation to 4 degrees or less with a mean length of 2.8 degrees (+/-0.15 sem). In this "short field" group, 18% had fields of 1 degrees or less. We observed 7 cells with rapid initial spatial summation up to 1 degree, followed by clear end zone inhibition. It has been recently suggested on the basis of localised inactivation experiments, that layer VI cells with long (greater than 8 degrees) fields may provide the drive to inhibitory interneurones in layer IV generating hypercomplex cell end zone inhibition. This observation is difficult to equate with evidence indicating that hypercomplex cell end zone inhibition reflects a mechanism showing maximal summation at lengths in the region of 2.8 degrees.(ABSTRACT TRUNCATED AT 250 WORDS)

Spikes, synchrony, and attentive learning by laminar thalamocortical circuits

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Corticothalamic interactions in the transfer of visual information

“…Indeed, in layer 6 as a whole short field cells predominate (Grieve & Sillito 1991a, 1995a. One factor stands out from all the available evidence: both the simple and complex cells projecting to the LGN tend to be strongly directionally sensitive.…”

End stopping in V1 is sensitive to contrast

“…both end stopping and length summation are observed in complex cells [12][13][14] , this notion presents a paradox, unless we assume that these computations occur at the antecedent to the simple-cell stage. Here we show that the well-known phenomenon of end stopping shows selectivity for sign of contrast, which would endow end-stopped cells with the ability to distinguish between contrast-conserving and contrast-reversing junctions and could therefore provide information essential for grouping in depth and border ownership.…”