“…Other lead-free piezoelectric materials that are biocompatible, such as polyvinylidene fluoride (PVDF) and barium titanate (BaTiO 3 ), have been investigated, however their piezoelectric constants are significantly lower compared to the conventional PZT. Additionally, also AlN-based PMUTs and CMUTs have been studied, although AlN PMUTs feature good piezoelectric properties, their operation frequency is larger, thus determining a higher ultrasound attenuation along its travelling path; CMUTs, on the other hand, support traditional ultrasound frequencies, in the range of a few-to-tens of MHz while also allowing seamless integration in CMOS processes [136]. The main disadvantage of CMUTs is the required higher bias voltage, which can reach more than 100 V and is clearly not suitable for wearable or implantable applications where a low-voltage source like a battery needs to be used instead: the need for high external bias voltages, however, can be eliminated by creating a built-in bias voltage through charge trapping Al 2 O 3 layer inside the CMUT [136].…”