The Lysozyme Content of Tears*

Tear Lipocalin and Lysozyme in Sjögren and Non-Sjogren Dry Eye

“…A total of 76 subjects [26 NDE controls,25 Sjogrens subjects (SS) and 25 non-Sjogrens keratoconjunctivitis sicca (KCS)] subjects were enrolled in this study. All subjects underwent a clinical evaluation visit to determine entry eligibility, before a second visit in which tear samples were collected.…”

Tear lysozyme levels in bacterial, fungal and viral corneal ulcers

“…2, r = -0.82), indicating that the decrease in the values of tear lysozyme occurs as a result of dilution of tears rather than due to the effect of causative agents like bacteria, viruses and fungi, as also suggested by Regan (1950). Since the levels of tear lysozyme were found to be reduced as a result of the increase in the rate of tear flow, the study may indicate that the lysozyme production remains constant during different corneal ulcerative diseases.…”

“…The mean levels of tear lysozyme in patients with bacterial and viral corneal ulcers were significantly less ( P < 0.05) when compared with healthy controls (Table 2). Regan (1950) observed low levels of tear lysozyme in acute conjunctivitis, corneal ulcres and iridocyclitis. Sapse et al (1968) reported low levels of tear lysozyme in subjects who had symptoms of smog eye irritation, which recovered after the patients were removed from the polluted environment.…”

Tear Function Parameters in Keratoconjunctivitis sicca with and without the Association of Sjögren’s Syndrome

“…All these proteins are major com ponents of the lacrimal fluid. Their presence under both normal and pathological condi tions has been well documented [5,9]. The tear proteins are synthesized by the lacrimal gland [ 10].…”