The major aeroallergens in Guangxi, China

Chen, Ke; Liao, Yuanfen; Jin-tan, Zhang

doi:10.1111/j.1365-2222.1988.tb02910.x

Cited by 12 publications

(4 citation statements)

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“…Guangxi Zhuang Autonomous Region, inhabited by the Du’an goat, is in the south subtropical zone, where the average annual temperature is 17–23 Celsius degree, the average maximum temperature is about 29 Celsius degree in July [ 41 ]. In the genome-wide screen, we found a very strong selective signal with a high-frequent nonsynonymous SNPs in MTOR (c.G5507C:p.G1836A).…”

Section: Discussionmentioning

confidence: 99%

Identification of Genomic Characteristics and Selective Signals in a Du’an Goat Flock

Chen

Wang

Sun

et al. 2020

Animals

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The Du’an goat is one of the most important farm animals in the Guangxi Autonomous Region of China, but the genetic basis underlying its adaptive traits has still not been investigated. Firstly, in this study, the genomes of 15 Du’an goats from a breeding farm were sequenced (mean depth: 9.50X) to analyze the patterns of genetic variation. A comparable diversity (17.3 million single nucleotide polymorphisms and 2.1 million indels) was observed to be associated with a lower runs of homozygosity-based inbreeding coefficient and smaller effective population size in comparison with other breeds. From selective sweep and gene set enrichment analyses, we revealed selective signals related to adaptive traits, including immune resistance (serpin cluster, INFGR1, TLR2, and immune-related pathways), body size (HMGA2, LCOR, ESR1, and cancer-related pathways) and heat tolerance (MTOR, ABCG2, PDE10A, and purine metabolism pathway). Our findings uncovered the unique diversity at the genomic level and will provide the opportunities for improvement of productivity in the Du’an goat.

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Section: Discussionmentioning

confidence: 99%

Identification of Genomic Characteristics and Selective Signals in a Du’an Goat Flock

Chen

Wang

Sun

et al. 2020

Animals

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“…The most important being Japanese cedar followed by pine [73, 74]. Artemisia , Casuarinaceae, Euphorbiaceae, Graminae, Moraceae and Pinaceae are the major contributors to the atmosphere of China [75]. Chen and Huang [76] observed that in Taiwan the tree species contribute 56 percent of the total pollen count.…”

Section: Introductionmentioning

confidence: 99%

An aerobiological perspective in allergy and asthma

Singh

Mathur

2012

Asia Pac Allergy

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Allergic diseases are amongst the most common chronic disorders worldwide. Today, more than 300 million of the population is known to suffer from one or other allergic ailments affecting the socio-economic quality of life. Major causative agents implicated are pollen grains, fungal spores, dust mites, insect debris, animal epithelia, etc. Several aerobiological studies have been conducted in different parts of the world to ascertain aerial concentration and seasonality of pollen grains and fungi. Especially from clinical point of view, it is important to know the details about the pollen season and pollen load in the atmosphere. The flowering time of higher plants are events that come periodically in each season, but the time of blooming may differ from year to year, in different geographic locations. Based on differences recorded in several years of observations in airborne pollen, pollen calendars are drawn as an aid to allergy diagnosis and management. This review article emphasises on various aerobiological parameters of environmental pollen from different parts of the world with special emphasis from India. The role of aerobiology in the diagnosis and management of allergic diseases is reviewed briefly in this article.

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“…These data suggest that there is different immunogenicity between dust mites and other allergens such as mugwort pollen. Mugwort is one of the most common pollen allergens in China (30,31). Allergic immune responses to the major mugwort pollen allergen Art, which belongs to the pectate lyase allergen family, are characterized by IgE binding and T-cell proliferation (32)(33)(34).…”

Section: Discussionmentioning

confidence: 99%

Increased expression of type 2 innate lymphoid cells in pediatric patients with allergic rhinitis

et al. 2019

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Type 2 innate lymphoid cells (ILC2s) are a newly identified group of innate immune cells. ILC2s promote features of allergic airway diseases through the secretion of Th2 type cytokines, including interleukin (IL)-4, IL-5 and IL-13. It remains unknown whether ILC2s aggregate in the peripheral blood. The present study examined the ILC2 levels in pediatric patients with allergic rhinitis (AR), and the correlation with the severity of clinical symptoms. Flow cytometry detected the ILC2s frequency in the peripheral blood of 12 healthy controls (HCs), 12 patients with AR sensitized only to house dust mites (HDM-AR), and 18 AR patients monosensitized to other antigens including weeds, animal danders and Blattella germanica, but not including HDM (non-HDM-AR). Clinical symptoms of AR were expressed according to the Total 5 Symptom Score (T5SS). The percentages of ILC2s in the peripheral blood were increased significantly in patients with HDM-AR and non-HDM-AR, compared with that in the HCs. A subgroup analysis of patients with AR indicated that the proportion of ILC2s was significantly increased in HDM-AR in comparison with that in non-HDM AR. Furthermore, there was a notable correlation between ILC2 levels and T5SS scores. ILC2s frequencies in PBMC were increased significantly in pediatric patients with AR, irrespective of the type of allergen. HDM may trigger more severe allergic reactions and an increase in the number of ILC2s. These discoveries indicate the unique function of ILC2 in AR and provide a potential therapeutic target.

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The major aeroallergens in Guangxi, China

Cited by 12 publications

References 0 publications

Identification of Genomic Characteristics and Selective Signals in a Du’an Goat Flock

Identification of Genomic Characteristics and Selective Signals in a Du’an Goat Flock

An aerobiological perspective in allergy and asthma

Increased expression of type 2 innate lymphoid cells in pediatric patients with allergic rhinitis

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