The management of macular hole retinal detachment and macular retinoschisis in pathological myopia; a UK collaborative study

Laviers, Heidi; Li, Ji-Peng Olivia; Grabowska, Anna; Charles, Stephen; Charteris, David G.; Haynes, Richard; Laidlaw, D A H; Steel, David; Yorston, David; Williamson, Tom H.; Zambarakji, Hadi

doi:10.1038/s41433-018-0166-4

Cited by 10 publications

(7 citation statements)

References 58 publications

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“…PM with macular hole RD is common in the Chinese population [ 30 ]. Like previously reported, they had some unique characteristics: delayed presentation, slow progression, and worse functional and anatomic prognosis [ 31 ], requiring second or combined surgery [ 28 , 30 ]. Surgery on the PM patient with macular hole RD was suspended during the COVID-19 pandemic because most ophthalmologists and patients preferred follow-up until the visual symptoms were aggregated.…”

Section: Discussionmentioning

confidence: 90%

The impact of the COVID-19 pandemic lockdown on rhegmatogenous retinal detachment services—Experiences from the Tongren eye center in Beijing

Zhao

She

et al. 2021

PLoS ONE

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Purpose To investigate the impact on services for rhegmatogenous retinal detachment (RRD) patients during the COVID-19 (2019coronal virus disease) pandemic in one tertiary center in Beijing. Methods A retrospective cohort study. Two reviewed consecutive RRD patients cohorts of the same length were treated during two different periods: the COVID-19 pandemic and the pre-COVID-19 group. The characteristics of patients, surgery, anesthesia methods, length of hospital stay, and the latest follow-up were recorded and analyzed. Results There were 79 patients in the COVID-19 pandemic group with a 55.9% reduction (179). Compared to patients in the pre-COVID-19, patients in the COVID-19 pandemic had a longer presurgical waiting times (28days, 3days, p<0.001), a higher percentage of patients with presurgical poor (less than 0.02) visual acuity (55.7%, 32.4%, p = 0.009), and a higher percentage of patients with presurgical choroidal detachment (34.2%, 19.6%, p = 0.01). There was no significant difference in the severity of presurgical proliferative vitreoretinopathy between the two groups (p = 0.64). Surgeries on pathological myopia patients with macular hole retinal detachment were postponed in the COVID-19 pandemic. There was a lower percentage of scleral buckling (27.8%, 41.3%, p = 0.02) and a lower rate of subretinal fluid drainage (45.4%, 75.7%, p = 0.01) in the COVID-19 pandemic. There was no significant difference in either postoperative visual acuity (p = 0.73) or the rate of single-surgery retinal attachment (p = 1) between the two groups. Patients in the COVID-19 pandemic had a shorter length of hospital stay (3hours, 35 hours, p<0.001), and a lower percentage of patients received general anesthesia (48.1%, 83.2%, p<0.001). None was infected with COVID-19 disease during the pandemic. Conclusion The COVID-19 pandemic lockdown caused prolonged presurgical waiting times, shorter hospital stays, less general anesthesia, and a significant reduction of RRD surgeries. The RD were more complicated, the surgeons were more conservative on procedures and patients selection, while the surgery outcomes were comparable.

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Section: Discussionmentioning

confidence: 90%

The impact of the COVID-19 pandemic lockdown on rhegmatogenous retinal detachment services—Experiences from the Tongren eye center in Beijing

Zhao

She

et al. 2021

PLoS ONE

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“…Vitrectomy is the most popular surgical procedure for MTM including retinoschisis and macular hole [ 16 , 17 ]. However, few studies have focused on the surgical management of FD.…”

Section: Discussionmentioning

confidence: 99%

Long-term surgical outcomes and prognostic factors of foveal detachment in pathologic myopia: based on the ATN classification

Feng

Zhou

et al. 2022

BMC Ophthalmol

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Background To investigate the long-term surgical outcomes and prognostic factors of foveal detachment (FD) in pathological myopia. Methods This retrospective observational study included 59 patients with FD (61 eyes) who underwent pars plana vitrectomy at Shanghai General Hospital between June 2017 and July 2018 with follow-up for at least 24 months. Comprehensive ophthalmic examinations, including best-corrected visual acuity (BCVA) and swept-source optical coherence tomography, were assessed. Preoperative myopic maculopathy was evaluated according to the ATN classification. Results FD completely resolved in 59 of 61 eyes (96.7%). Mean duration of retinal reattachment was 12.10 ± 8.10 months. Mean logMAR BCVA improved from 1.34 ± 0.52 to 0.83 ± 0.43 at 24 months postoperatively (P < 0.001). Secondary macular hole occurred in 8 eyes (13.1%) with a mean period of 3.4 ± 4.1 weeks after primary surgery. In regression analyses, baseline myopic atrophy maculopathy (MAM) (B = 0.213, P = 0.005) and vitreomacular traction (VMT) (B = 0.292, P = 0.007) were adverse prognostic factors for postoperative BCVA. A more severe MAM revealed a delay in retinal reattachment (B = 5.670, P = 0.002). FD eyes with VMT (OR = 1.309, P = 0.003) or outer lamellar macular hole (O-LMH) (OR = 1.369, P < 0.001) were risk factors for postoperative secondary macular hole. Conclusions Vitrectomy was effective in the long-term for treating FD. Careful consideration is needed for those with VMT or O-LMH due to the high risk of secondary macular hole after vitrectomy. FD eyes with more severe MAM tended to have poorer postoperative BCVA and extended periods of retinal reattachment.

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“…In the retina, structural damage almost always precedes functional damage. RNFL thinning found in idiopathic macular holes may lead to retinal detachment, 27,28 a pathological mechanism reported in patients with early‐stage glaucoma 7 . Another study reported reduced thickness of RNFL and GCIPL in idiopathic retinal telangiectasia, a neurodegenerative retinal disease characterized by alterations in the macular capillary network, neurosensory atrophy, and occasional subretinal neovascularization 29 .…”

Section: Discussionmentioning

confidence: 99%

Risk of retinal disease in patients with bipolar disorder: A nationwide cohort study

Hsu

Bai

Tsai

et al. 2022

Psychiatry Clin Neurosci

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Aims: Patients with brain diseases have been associated with several retinal abnormalities. This study aimed to assess the risk of retinal diseases in patients with bipolar disorder (BD).Methods: This nationwide cohort of 73,271 patients with BD was enrolled between 2001 and 2009. To identify newly diagnosed retinal diseases, the patients were followed to the end of 2011. The control group included 293,084 patients, matched for demographic characteristics and medical and ophthalmological comorbidities. The Kaplan-Meier method was used to estimate incidence rates of retinal diseases. Cox regression was applied to calculate the hazard ratios (HRs) with 95% confidence intervals (CIs) after adjusting for confounders.Results: Patients with BD had higher incidence rates of any retinal disease than the controls (1.27% vs 0.48%, P < 0.001), and retinal diseases were diagnosed at a young age (54.23 years [AE12.68 years] vs 57.01 years [AE13.12 years], P < 0.001). After adjusting for demographic characteristics, physical and ophthalmological comorbidities, and medications, the HR was 3.24 (95% CI, 2.18-4.82) for retinal detachment, 2.35 (95% CI, 1.83-3.03) for primary retinopathy, 2.26 (95% CI, 1.91-2.68) for diabetes retinopathy, 2.39 (95% CI, 1.49-3.82) for hypertensive retinopathy, and 3.46 (95% CI, 2.45-4.89) for retinal vascular complications in patients with BD vs controls. The cumulative daily dose of bipolar medications was not associated with the incidence of any retinal disease. Conclusion:Patients with BD were associated with a higher risk of retinal detachment, primary retinopathy, diabetes retinopathy, hypertensive retinopathy, and retinal vascular complications than the controls. Further studies are needed to examine the mechanisms mediating these retinal diseases in patients with BD.

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The management of macular hole retinal detachment and macular retinoschisis in pathological myopia; a UK collaborative study

Abstract: PPV is the only surgical procedure performed for the management of MHRD and MRS amongst the study participants. Success rates and visual outcomes are limited for MHRD and consistent with the current literature for MRS.

Cited by 10 publications

References 58 publications

The impact of the COVID-19 pandemic lockdown on rhegmatogenous retinal detachment services—Experiences from the Tongren eye center in Beijing

The impact of the COVID-19 pandemic lockdown on rhegmatogenous retinal detachment services—Experiences from the Tongren eye center in Beijing

Long-term surgical outcomes and prognostic factors of foveal detachment in pathologic myopia: based on the ATN classification

Risk of retinal disease in patients with bipolar disorder: A nationwide cohort study

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