The Measurement of Focal Diurnal Variation in the Femoral Articular Cartilage of the Knee

Abstract

Abstract.Our objective was to test the hypothesis that focal diurnal changes occur in the femoral articular cartilage of the knee in asymptomatic young adults. Six volunteers each were scanned early in the morning, and at the end of a working day spent mainly standing. This protocol was repeated on three successive weeks. Femoral cartilage segmentations were obtained using a region-growing algorithm. These segmentations then were regridded onto a 500-pixel template, and differences in the resulting thickness maps were assessed. Analysis of variance showed no significant diurnal variation in mean thickness. There were, however, statistically-significant diurnal changes in the thickness maps. Cartilage thickness decreased during the day in three specific locations which suffer the greatest biomechanical force.

Templates of the cartilage layers of the patellofemoral joint and their use in the assessment of osteoarthritic cartilage damage

“…For example, in studying the cartilage thickness across the distal femoral surfaces, Shepherd and Seedhom compared condylar region values with those in the trochlear region 26 and Karvonen et al compared thicknesses at weight-bearing sites with those at non-weightbearing sites 32 . A second approach is to use anatomic landmarks to establish a correspondence between different data sets, as Brett et al and Waterton et al did when they used an automatic landmark generation algorithm to create sets of corresponding landmarks on each of the slice contours of segmented MR images 33,34 . A third approach comparing unrelated articular surface geometries is to characterize them in terms of geometric primitives so that the surfaces can then be compared in terms of parameters the primitives 35 .…”

The effect of ovariectomy on mandibular cortical thickness in the rat

“…[18][19][20] These methods have been used very effectively in previous studies to provide robust and accurate solutions to challenging image analysis problems. 21,22 The interface, used in the present study, allowed the user to position points on the boundary of the cortical bone in the mandible. Future automatic location of the borders of the cortical bone would provide a number of advantages over purely manual measurements.…”

Construction of 3D Shape Models of Femoral Articular Cartilage Using Harmonic Maps

“…The connectivity of each pointset is generated from its contour representation using the algorithm of Geiger [8]. Our motivation for this is to be able to produce corresponded thickness maps [4] of pre-segmented cartilage from 3D MR images.…”