“…Moreover, we found a significant increase in NADH production with age in the presence of the glycosylfructose energy substrate turanose. Turanose is hydrolysed to glucose and fructose by α-glucosidase, indicating a link between turanose and fructose metabolism ( Julio-Gonzalez et al., 2021 ; Tewari and Goldberg, 1991 ; Zagalak and Curtius, 1975 ). Turanose metabolism increased in the control cohort with age ( p =0.0072 and r =0.6755) ( Fig.…”