The aim of our study is to investigate the mediating role of self-compassion in the relationship between authenticity and alexithymia by examining the relationships between authenticity, alexithymia and self-compassion. The data collected via email by using three scales from the students of a foundation university in Istanbul/Turkey in the spring semester of 2022–2023. The data collection method was a descriptive cross-sectional study and the data were collected on a voluntary basis. Since it was thought that there would be a difference between the departments, data were collected from three different departments. The sample included 263 participants, 139 were English Language Teaching, 107 were Guidance and Psychological Counseling, and 17 were Elementary Mathematics Teaching students. The average age of the participants was 22.11 ± 3.59, 257 of them were single and 6 of them were married. The data were evaluated by using the SPSS 22.0 and LISREL 8.80 programs. While descriptive analyses were used in the evaluation, the mediating role of self-compassion in the relationship between authenticity and alexithymia was tested with Structural Equation Modeling. When the measurement model was examined, it was seen that there was a relationship between authenticity and alexithymia (r = −.40; p < .000), between self-compassion and alexithymia (r = − .85; p < .001) and between self-compassion and authenticity (r = .43; p < .001). When the structural equation model was examined, it was found that the relationship between authenticity and alexithymia in the measurement model (r = −.40) decreased to (β = − .05; p > .005) when the mediating role of self-compassion was examined and the relationship was found to be insignificant. When this path was removed from the model and the model was re-examined, the goodness of fit values of the model were χ2/df (71.12/51) ratio = 1.174; RMSEA = .039; SRMR = .050; CFI= .99; NFI = .96; NNFI = .98; IFI = .99; RFI = .95 and GFI = .96. In the study, it was found that self-compassion has a full mediating role in the relationship between authenticity and alexithymia in three departments. The relationship between authenticity and alexithymia goes through self-compassion.