The Mediterranean Diet Benefit on Cardiovascular Hemodynamics and Erectile Function in Chronic Heart Failure Male Patients by Decoding Central and Peripheral Vessel Rheology

Angelis, Athanasios; Chrysochoou, Christina; Tzorovili, Evangelia; Laina, Aggeliki; Xydis, Panagiotis; Terzis, Ioannis; Ioakeimidis, N.; Aznaouridis, Konstantinos; Vlachopoulos, Charalambos; Tsioufis, Κonstantinos

doi:10.3390/nu13010108

Cited by 13 publications

(9 citation statements)

References 35 publications

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“…These findings could be explained by the high use of pesticides in China and Hong Kong, where all three studies reporting neutral or negative results were conducted, although this hypothesis cannot be confirmed. More general concepts of healthy dietary habits 42 or organic food consumption 43 were also reported to be associated with a lower prevalence or development of ED, as was adherence to the Mediterranean diet, most commonly assessed through food‐frequency questionnaires 44–47 . Flavonoid‐rich foods 35,48 and nuts 38,47 were also consumed more frequently by those who did not have ED, likely reflecting a Mediterranean dietary pattern.…”

Section: Resultsmentioning

confidence: 99%

Effects of diet and antihyperglycemic drugs on erectile dysfunction: A systematic review

et al. 2022

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Background: Erectile dysfunction is recognized as one of the complications of diabetes mellitus. To date, a wide gap of knowledge is present on the efficacy of pharmacological treatments of diabetes mellitus on erectile function, acting not only through metabolic control. Similarly, the effects of different diet regimens on erectile dysfunction are still debated. Objectives:We aimed to explore the effects of diet and antihyperglycemic drugs, considering both old and novel therapeutic approaches, on erectile function. Materials/methods:We performed a systematic review, following the PRISMA guidelines. The research was conducted on studies reporting erectile dysfunction assessment in subjects with diabetes and the relationship with diet and antihyperglycemic drugs. Results:The Mediterranean diet was effective in most studies for the protection of erectile function. Furthermore, antihyperglycemic drugs seem to show an overall protective role on erectile function.Discussion/conclusion: Although encouraging results are present for all classes of antihyperglycemic drugs, several studies are needed in humans, mainly on acarbose, pioglitazone, dipeptidyl-peptidase-4 inhibitors, and sodium-glucose cotransporter-2 inhibitors.

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Section: Resultsmentioning

confidence: 99%

Effects of diet and antihyperglycemic drugs on erectile dysfunction: A systematic review

et al. 2022

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“…This study results indicated that participants with intermediate adherence to the Mediterranean diet (3 < MDS ≤ 6) had significantly lower odds of COVID-19 incidence (multivariable-adjusted OR = 0.50, 95% CI: 0.34–0.73), and those with the highest adherence (MDS > 6) had the lowest risk (multivariable-adjusted OR = 0.36, 95% CI: 0.16–0.84, p for trend < 0.001) as compared with subjects with MDS ≤ 3. Angelis et al [ 46 ]. mentioned that adherence to the Mediterranean diet has a main impact on cardiovascular diseases and other cardio - metabolic disorders, like diabetes that predisposes to COVID-19 infection and related outcomes.…”

Section: Discussionmentioning

confidence: 99%

Adherence to the Mediterranean Diet Association with Serum Inflammatory Factors Stress Oxidative and Appetite in COVID-19 Patients

2023

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Background and Objectives: The Mediterranean diet’s bioactive components are suggested to strengthen the immune system and to exert anti-inflammatory actions. This study investigated the association between adherence to the Mediterranean diet with serum inflammatory factors, total antioxidant capacity, appetite, and symptoms of COVID-19 patients. Materials and Methods: This cross-sectional study was conducted among 600 Iranian COVID-19 patients selected by a simple random method. The ten-item Mediterranean diet adherence questionnaire was used to assess diet adherence. At the beginning of the study, 5 cc of blood was taken from all patients for measurement of serum interleukin 1β) IL-1β), tumor necrosis factor (TNF-α), malondialdehyde (MDA), high sensitivity C-reactive protein (hs-CRP) and total antioxidant capacity (TAC). A human ELISA kit with serial number 950.090.096 produced by the Diaclone Company was used to test this cytokine using the sandwich ELISA method. Results: One hundred and five patients presented a high adherence and 495 patients presented a low adherence to the Mediterranean diet. The incidence of fever, cough, diarrhea, taste changes, and pneumonia severity index were significantly lower in patients who adhered to the Mediterranean diet more than other patients. Serum levels of tumor necrosis factor (5.7 ± 2.1 vs. 6.9 ± 2.8 p = 0.02), interleukin 1 beta (3.2 ± 0.02 vs. 4.9 ± 0.01 p = 0.02), high-sensitivity C-reactive protein (17.08 ± 4.2 vs. 19.8 ± 2.5 p = 0.03), and malondialdehyde (5.7 ± 0.2 vs. 6.2 ± 0.3 p = 0.02) were significantly lower in patients who adhered more to the Mediterranean diet than other patients. Conclusion: The Mediterranean diet can improve the symptoms and elevated serum inflammatory factors in COVID-19 patients, so clinical trial studies are suggested to confirm this effect.

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“…In experimental models, olive oil, a primary substance in the Mediterranean diet, reduced infarct size and protected reperfused myocardium from oxidative damage in vivo. Hyperproteinic, low-carbohydrate, and low-fat diets also demonstrate positive effects on functional capacity; however, RCTs in secondary prevention are scarce [ 45 , 46 , 47 ]. Nutritional education seems to be important for HF patients in order to sustain fluid and salt balance and prevent cachexia through a balanced diet.…”

Section: Nutritional Issues In Chronic Hfmentioning

confidence: 99%

Fluid and Salt Balance and the Role of Nutrition in Heart Failure

et al. 2022

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The main challenges in heart failure (HF) treatment are to manage patients with refractory acute decompensated HF and to stabilize the clinical status of a patient with chronic heart failure. Beyond the use of medications targeted in the inhibition of the neurohormonal system, the balance of salt and fluid plays an important role in the maintenance of clinical compensation in respect of renal function. In the case of heart failure, a debate of opinion exists on salt restriction. Restricted dietary sodium might lead to worse outcomes in heart failure patients due to the activation of the neurohormonal system and malnutrition. On the contrary, positive sodium balance is the primary driver of water retention and, ultimately, volume overload in acute HF. Some recent studies reported associations of decreased salt consumption with higher readmission rates and increased mortality. Thus, the usefulness of salt restriction in heart failure management remains debated. The use of individualized nutritional support, compared with standard hospital food, was effective in reducing these risks, particularly in the group of patients at high nutritional risk.

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The Mediterranean Diet Benefit on Cardiovascular Hemodynamics and Erectile Function in Chronic Heart Failure Male Patients by Decoding Central and Peripheral Vessel Rheology

Cited by 13 publications

References 35 publications

Effects of diet and antihyperglycemic drugs on erectile dysfunction: A systematic review

Effects of diet and antihyperglycemic drugs on erectile dysfunction: A systematic review

Adherence to the Mediterranean Diet Association with Serum Inflammatory Factors Stress Oxidative and Appetite in COVID-19 Patients

Fluid and Salt Balance and the Role of Nutrition in Heart Failure

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