The medium effect and activity coefficient of the hydrogen ion in 1,4-dioxane-water mixtures

Titrations in nonaqueous solvents

“…The system assumes, in common with the Hammett concept, that the ratio of the activity coefficients of the acid and base forms of the acetal is constant in a given solvent medium. Data taken in dioxane-water mixtures support the method (111). In another approach, a function based on the Ostwald dilution law has been suggested as a way of describing quantitatively the ability of a Bronsted acid to transfer a proton to any solvent, or of a Bronsted base to remove a proton from an acidic solvent (139).…”