The merits of cell salvage in arthroplasty surgery: an overview

Dusik, Chris J.; Hutchison, Carol; Langelier, David

doi:10.1503/cjs.026612

Cited by 18 publications

(10 citation statements)

References 17 publications

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“…This is consistent with other studies in joint replacement surgery that consistently show that intraoperative cell salvage usage reduces PRBC transfusion. (Bridgens et al , ; Dusik et al , ). The 2006 cochrane collaboration of meta‐analysis in intraoperative cell salvage found its use in joint surgery not only to be associated with less allogeneic PRBC but also to have no increase in morbidity or mortality (Carless et al , ).…”

Section: Discussionmentioning

confidence: 99%

Preoperative anaemia is associated with increased allogeneic pack red cell transfusion in revision hip and knee joint arthroplasty: a retrospective analysis of 5387 patients over a 10‐year period at a single high volume centre

Kasivisvanathan

Ramesh

Baikady

et al. 2016

Transfusion Medicine

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There were 5387 patients assessed of which 3021 (56·01%) patients had revision total hip replacements and 2366 (43·09%) had revision total knee arthroplasty. Of these patients 1956 (36·03%) had preoperative WHO defined anaemia. A total of 2034 (37·08%) patients received at least one unit of allogeneic PRBC during their primary hospital admission. In the final model preoperative WHO defined anaemia was independently associated with allogeneic PRBC transfusion in hip and knee revision surgery OR 4·042 (4·012-4·072 95% CI) CONCLUSIONS: Preoperative anaemia is common in patients presenting for revision hip and knee arthroplasty and independently associated with transfusion of allogeneic PRBC.

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Section: Discussionmentioning

confidence: 99%

Preoperative anaemia is associated with increased allogeneic pack red cell transfusion in revision hip and knee joint arthroplasty: a retrospective analysis of 5387 patients over a 10‐year period at a single high volume centre

Kasivisvanathan

Ramesh

Baikady

et al. 2016

Transfusion Medicine

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“…Unwashed blood revealed poor results as it may contain hemolyzed RBC, clotting factors and cytokines[ 110 , 111 ]. Therefore, cell separation and washing showed better results with an autologous red cell concentrate with normal function and no complications[ 112 ].…”

Section: Intra-operativementioning

confidence: 99%

Perioperative blood management strategies for patients undergoing total knee replacement: Where do we stand now?

Themistoklis¹,

Vogiatzaki²,

Kazakos³

et al. 2017

WJO

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Total knee replacement (TKR) is one of the most common surgeries over the last decade. Patients undergoing TKR are at high risk for postoperative anemia and furthermore for allogeneic blood transfusions (ABT). Complications associated with ABT including chills, rigor, fever, dyspnea, light-headedness should be early recognized in order to lead to a better prognosis. Therefore, perioperative blood management program should be adopted with main aim to reduce the risk of blood transfusion while maximizing hemoglobin simultaneously. Many blood conservation strategies have been attempted including preoperative autologous blood donation, acute normovolemic haemodilution, autologous blood transfusion, intraoperative cell saver, drain clamping, pneumatic tourniquet application, and the use of tranexamic acid. For practical and clinical reasons we will try to classify these strategies in three main stages/pillars: Pre-operative optimization, intra-operative and post-operative protocols. The aim of this work is review the strategies currently in use and reports our experience regarding the perioperative blood management strategies in TKR.

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“…3 The intraoperative blood salvage procedure collects the shed blood and washes and filters it before returning it to the patient. 4,5 Intraoperative blood salvage has been shown to reduce the need for allogeneic transfusions in bleeding operative patients, 6 and it avoids some of the adverse effects of allogeneic transfusion including RBC alloimmunization, certain transfusion reactions, and the transmission of several infectious agents. It might also be accepted by patients who refuse allogeneic transfusion.…”

Section: Level Of Evidence: IImentioning

confidence: 99%