The metabolic syndrome in an Arab population: a first look at the new International Diabetes Federation criteria

Harzallah, F.; Alberti, Hugh; Khalifa, F. Ben

doi:10.1111/j.1464-5491.2006.01866.x

Cited by 80 publications

(69 citation statements)

References 9 publications

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“…These results confirmed previous findings in Tunisian population [5][6][7]17 as well as in others population [18][19][20][21] . Sedentary lifestyle, the lack of participation in physical activities among adult Tunisian women, hormonal factors and postmenopausal weight gain may prove the large waist circumference in women 22,23 .…”

Section: Discussionsupporting

confidence: 82%

Untitled

2016

IJPSR

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Metabolic syndrome (MS) is a multi-factorial disorder with insulin resistance as a major characteristic. Adiponectin, an adipocyte derived cytokine, can regulate glucose levels and lipid homeostasis by its insulin sensitizer properties. Low circulating levels of serum adiponectin has been reported as a risk factor for the development of MS. The aim of this case control study was to investigate the association of serum adiponectin concentration, insulin resistance and various risk factors with MS among Tunisian participants. We designed a case-control study involving 100 patients with MS (84 females and 16 males, mean age 54±11 years) and 100 healthy controls (60 females and 40 males, mean age 51±10 years). Serum total cholesterol and triglyceride were determined by enzymatic methods. Insulin resistance was calculated using the homeostasis model assessment (HOMA-IR) = fasting insulin (uU/ml) x fasting plasma glucose (mmol/l)/22.5 and serum adiponectin levels were measured by enzyme-linked immunosorbent assay. Interestingly, 72% of the subjects with MS had high blood pressure. Compared with controls, patients had significantly higher levels of triglycerides (1.64±0.88 mmol /l; 1.07±0.43 mmol/l; p=0.03) and lower levels of high-density lipoprotein cholesterol (1.26±0.41 mmol/l; 1.58±0.30 mmol/l; p=0.04). In addition, there was a significant difference in serum adiponectin levels between the subjects with MS and controls (13.96±5.23 µg/ml; 22.24±9.07 µg/ml; p=0.006) and the mean levels of HOMA-IR were 5.23±3.52 and 1.83±0.93 for patients and controls, respectively. In conclusion, hypoadiponectinemia and insulin resistance represent risk factors for MS development.

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Section: Discussionsupporting

confidence: 82%

Untitled

2016

IJPSR

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“…The MetS prevalence estimated in the current study is similar to that reported in a previous study carried out in a population of Greater Tunis, located in the north of Tunisia (10) . Several studies have reported an increased rate of MetS in women compared with men (8,10,21,22) . In the present study the higher MetS prevalence in women could be explained by the fact that central obesity was three times more frequent in women than in men (65?5 % v. 20?6 %, respectively).…”

Section: Discussionmentioning

confidence: 99%

Prevalence and determinants of the metabolic syndrome among Tunisian adults: results of the Transition and Health Impact in North Africa (TAHINA) project

Belfki¹,

Ali²,

Aounallah-Skhiri³

et al. 2012

Public Health Nutr.

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Objective: To determine the prevalence of metabolic syndrome (MetS) and its components and to evaluate the relationship between this diagnosis and cardiovascular risk factors, demographic and socio-economic variables. Design: A cross-sectional study using a questionnaire including information on sociodemographic and CVD risk factors. Blood pressure, anthropometric indices, fasting glucose and lipid profile were measured. MetS was defined according to the criteria of the National Cholesterol Education Program, Adult Treatment Panel III. Setting: The whole Tunisian territory; Transition and Health Impact in North Africa (TAHINA) project. Subjects: A total of 4654 individuals (1840 men and 2814 women), aged 35 to 74 years, who participated in the Tunisian national survey. Results: The overall prevalence of MetS was 30?0 %, higher in women (36?1 %) than in men (20?6 %; P , 0?001). In both genders MetS prevalence increased significantly with age (P , 0?001), but this increase was more important in women. Multiple regression analyses showed that the odds for MetS increased significantly with urban area for both men and women (P , 0?05 and P , 0?001, respectively). The multivariate models showed also that the odds for MetS increased significantly with increasing level of education and in those with a family history of CVD for men (both P , 0?05) and after the menopausal transition for women (P , 0?05). Conclusions: The study highlights the MetS problem in a middle-income developing country. There is an urgent need for a comprehensive, integrated, population-based intervention programme to ameliorate the growing problem of MetS in Tunisians.

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“…In Turkey, the prevalence of CMS syndrome (ATP criteria) did not differ between urban (33.8%) and rural (33.9%) population, while it did between adult males (28%) and females (39.6%) [28].…”

Section: Middle East and North Africamentioning

confidence: 99%

Cardio Metabolic Syndrome: A Global Epidemic

Kelli¹,

Kassas²,

Lattouf

2016

J Diabetes Metab

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Cardio Metabolic Syndrome (CMS), also known as insulin resistance syndrome or metabolic syndrome X, is a combination of metabolic disorders or risk factors that essentially includes a combination of diabetes mellitus, systemic arterial hypertension, central obesity and hyper-lipidemia. Common to these diseases of metabolism is the associated development of atherosclerotic cardiovascular disease (ASCVD). Studies have shown a strong link between CMS and increased prevalence of peripheral vascular diseases, coronary artery disease and myocardial infarctions as well as cerebro-vascular arterial diseases and stroke.

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The metabolic syndrome in an Arab population: a first look at the new International Diabetes Federation criteria

Cited by 80 publications

References 9 publications

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Prevalence and determinants of the metabolic syndrome among Tunisian adults: results of the Transition and Health Impact in North Africa (TAHINA) project

Cardio Metabolic Syndrome: A Global Epidemic

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