The microaerophily and photosensitivity of Propionibacterium acnes

Gribbon, E. M.; Shoesmith, J. G.; Cunliffe, W.J.; Holland, K. T.

doi:10.1111/j.1365-2672.1994.tb04405.x

Cited by 32 publications

(23 citation statements)

References 38 publications

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“…Propionibacterium acnes produces abundant porphyrins, which might contribute to skin damage (542). The interaction of porphyrins with oxygen is thought to contribute to keratinocyte damage and consequently to have implications regarding the pathogenesis of progressive macular hypomelanosis (543).…”

Section: Interactions Between Actinobacteria and Plantsmentioning

confidence: 99%

Taxonomy, Physiology, and Natural Products of Actinobacteria

Barka

Vatsa

Sanchez

et al. 2016

Microbiol Mol Biol Rev

1,600

1,048

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SUMMARYActinobacteriaare Gram-positive bacteria with high G+C DNA content that constitute one of the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and terrestrial ecosystems. ManyActinobacteriahave a mycelial lifestyle and undergo complex morphological differentiation. They also have an extensive secondary metabolism and produce about two-thirds of all naturally derived antibiotics in current clinical use, as well as many anticancer, anthelmintic, and antifungal compounds. Consequently, these bacteria are of major importance for biotechnology, medicine, and agriculture.Actinobacteriaplay diverse roles in their associations with various higher organisms, since their members have adopted different lifestyles, and the phylum includes pathogens (notably, species ofCorynebacterium,Mycobacterium,Nocardia,Propionibacterium, andTropheryma), soil inhabitants (e.g.,MicromonosporaandStreptomycesspecies), plant commensals (e.g.,Frankiaspp.), and gastrointestinal commensals (Bifidobacteriumspp.).Actinobacteriaalso play an important role as symbionts and as pathogens in plant-associated microbial communities. This review presents an update on the biology of this important bacterial phylum.

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Section: Interactions Between Actinobacteria and Plantsmentioning

confidence: 99%

Taxonomy, Physiology, and Natural Products of Actinobacteria

Barka

Vatsa

Sanchez

et al. 2016

Microbiol Mol Biol Rev

1,600

1,048

View full text Add to dashboard Cite

show abstract

“…acnes abundantly produces porphyrins, which might contribute to skin damage (156). The interaction of porphyrins with oxygen is thought to contribute to keratinocyte damage and consequently to have implications regarding the pathogenesis of progressive macular hypomelanosis (473).…”

Section: Interaction Of P Acnes With Its Environmentmentioning

confidence: 99%

“…Metabolic reconstruction revealed the capacity of P. acnes to cope with varying oxygen availability, in accordance with its growth under microaerobic as well as anaerobic conditions (96,156). The genome encodes all key components of oxidative phosphorylation, employing two terminal oxidases, a cytochrome aa 3 oxidase, a cytochrome d oxidase whose E. coli homolog predominates when cells are grown at low aeration, and an F 0 F 1 -type ATP synthase (46).…”

Section: P Acnes Genome and Biological Lifestylementioning

confidence: 99%

Genomics ofActinobacteria: Tracing the Evolutionary History of an Ancient Phylum

Ventura

Canchaya

Tauch

et al. 2007

Microbiol Mol Biol Rev

946

638

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SUMMARY Actinobacteria constitute one of the largest phyla among Bacteria and represent gram-positive bacteria with a high G+C content in their DNA. This bacterial group includes microorganisms exhibiting a wide spectrum of morphologies, from coccoid to fragmenting hyphal forms, as well as possessing highly variable physiological and metabolic properties. Furthermore, Actinobacteria members have adopted different lifestyles, and can be pathogens (e.g., Corynebacterium, Mycobacterium, Nocardia, Tropheryma, and Propionibacterium), soil inhabitants (Streptomyces), plant commensals (Leifsonia), or gastrointestinal commensals (Bifidobacterium). The divergence of Actinobacteria from other bacteria is ancient, making it impossible to identify the phylogenetically closest bacterial group to Actinobacteria. Genome sequence analysis has revolutionized every aspect of bacterial biology by enhancing the understanding of the genetics, physiology, and evolutionary development of bacteria. Various actinobacterial genomes have been sequenced, revealing a wide genomic heterogeneity probably as a reflection of their biodiversity. This review provides an account of the recent explosion of actinobacterial genomics data and an attempt to place this in a biological and evolutionary context.

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“…Data are presented in this supplement to suggest that the lipases of P. acnes may be central to this mechanism [28]. In-depth data will also be reported to indicate how P. acnes may produce inflammation.…”

Section: Aetiology Of Acnementioning

confidence: 99%