The Moderating Effects of Skin Color and Ethnic Identity Affirmation on Suicide Risk among Low-SES African American Women

Perry, Brea L.; Stevens‐Watkins, Danelle; Oser, Carrie B.

doi:10.1007/s12552-012-9080-8

Cited by 42 publications

(39 citation statements)

References 69 publications

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“…Studies noted stronger effects among African-American mothers. These variations may be due to differences in nicotine metabolism among racial groups and/or differences in smoking and exposure patterns [59] . Furthermore, certain populations with genetic polymorphisms may be more vulnerable to damage due to alterations in the metabolic pathways [60] .…”

Section: Birth Weightmentioning

confidence: 99%

Smoking-Induced Changes in the Maternal Immune, Endocrine, and Metabolic Pathways and Their Impact on Fetal Growth: A Topical Review

Sabra

Gratacós²,

Roig³

2017

Fetal Diagn Ther

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Perinatal maternal smoking exposure (PMSE) is one of the major environmental risk factors encountered by the fetus. PMSE is usually associated with adverse pregnancy outcomes that may manifest at different stages of life. Nevertheless, fetal growth restriction is the most common smoking-induced side effect. PMSE induces changes in the maternal multiple organ systems. These alterations may affect placentation, which subsequently affects fetal growth. It is worthy to note, however, that the extent of maternal smoking-induced changes depends mainly on the maternal level of susceptibility. Hence, the perinatal pregnancy outcomes vary depending on the interaction between the triad: the maternal, fetal, and placental modifications, making it more complex. In this review, we try to unveil the effect of smoking-induced maternal changes on the maternal immune, endocrine, and metabolic pathways and their impact on fetal growth.

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Section: Birth Weightmentioning

confidence: 99%

Smoking-Induced Changes in the Maternal Immune, Endocrine, and Metabolic Pathways and Their Impact on Fetal Growth: A Topical Review

Sabra

Gratacós²,

Roig³

2017

Fetal Diagn Ther

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“…Although the origin of the ALLO profile observed in AA women is unknown, it may reflect the greater chronic psychosocial stress experienced by AA women (Perry et al 2012; Perry et al 2013). While speculative at present, this hypothesis is consistent with an allostatic load model of blunted stress reactivity resulting from chronic stress, and data from animal models of chronic stress and diminished neurosteroid availability/synthesis (see below).…”

Section: Neurosteroid and Gabaergic Regulation Of The Hpa-axis: Acutementioning

confidence: 99%

Neurosteroid, GABAergic and hypothalamic pituitary adrenal (HPA) axis regulation: what is the current state of knowledge in humans?

Crowley

Girdler

2014

Psychopharmacology

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Rationale A robust epidemiological literature suggests an association between chronic stress and the development of affective disorders. However, the precise biological underpinnings of this relationship remain elusive. Central to the human response and adaptation to stress, activation and inhibition of the hypothalamic pituitary adrenal (HPA) axis involves a multi-level, multi-system, neurobiological stress response which is as comprehensive in its complexity as it is precarious. Dysregulation in this complex system has implications for human stress related illness. Objectives The pioneering research of Robert Purdy and colleagues has laid the groundwork for advancing our understanding of HPA-axis regulation by stress-derived steroid hormones and their neuroactive metabolites (termed neurosteroids), which are potent allosteric modulators of GABAA receptor function in the central nervous system. This review will describe what is known about neurosteroid modulation of the HPA-axis in response to both acute and chronic stress, particularly with respect to the current state of our knowledge of this process in humans. Results Implications of this research to the development of human stress related illness are discussed in the context of two human stress-related psychiatric disorders - major depressive disorder and premenstrual dysphoric disorder. Conclusions Neurosteroid-mediated HPA-axis dysregulation is a potential pathophysiologic mechanism which may cross traditional psychiatric diagnostic classifications. Future research directions are identified.

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“…These experiences may, in turn, foster behaviors that compromise the health of African American women. 41 In addition, negative societal stereotypes targeting African American women can unfavorably affect their sexual health. 42,43 The relationship between self-esteem and engaging in risky sexual behaviors 44 may be evident among some African American women who internalize negative stereotypes.…”

Section: Introductionmentioning

confidence: 99%

The Impact of Racism on the Sexual and Reproductive Health of African American Women

Prather

Fuller

Marshall

et al. 2016

Journal of Women's Health

143

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African American women are disproportionately affected by multiple sexual and reproductive health conditions compared with women of other races/ethnicities. Research suggests that social determinants of health, including poverty, unemployment, and limited education, contribute to health disparities. However, racism is a probable underlying determinant of these social conditions. This article uses a socioecological model to describe racism and its impact on African American women’s sexual and reproductive health. Although similar models have been used for specific infectious and chronic diseases, they have not described how the historical underpinnings of racism affect current sexual and reproductive health outcomes among African American women. We propose a socioecological model that demonstrates how social determinants grounded in racism affect individual behaviors and interpersonal relationships, which may contribute to sexual and reproductive health outcomes. This model provides a perspective to understand how these unique contextual experiences are intertwined with the daily lived experiences of African American women and how they are potentially linked to poor sexual and reproductive health outcomes. The model also presents an opportunity to increase dialog and research among public health practitioners and encourages them to consider the role of these contextual experiences and supportive data when developing prevention interventions. Considerations address the provision of opportunities to promote health equity by reducing the effects of racism and improving African American women’s sexual and reproductive health.

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The Moderating Effects of Skin Color and Ethnic Identity Affirmation on Suicide Risk among Low-SES African American Women

Cited by 42 publications

References 69 publications

Smoking-Induced Changes in the Maternal Immune, Endocrine, and Metabolic Pathways and Their Impact on Fetal Growth: A Topical Review

Smoking-Induced Changes in the Maternal Immune, Endocrine, and Metabolic Pathways and Their Impact on Fetal Growth: A Topical Review

Neurosteroid, GABAergic and hypothalamic pituitary adrenal (HPA) axis regulation: what is the current state of knowledge in humans?

The Impact of Racism on the Sexual and Reproductive Health of African American Women

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