The Morbidity and Mortality Risks following Percutaneous Coronary Interventions in Cirrhosis

Abstract

Background: The prevalence of coronary artery disease in cirrhotic population is estimated to be low and the risk of bleeding in those who had percutaneous catheterization interventions (PCI) is not well studied yet. Our aim in this study is to determine the morbidity and mortality risks in cirrhotic patient undergoing PCI.

Percutaneous Coronary Intervention Outcomes in Patients with Liver Cirrhosis: A Systematic Review and Meta-Analysis

“…Higher in-hospital mortality and vascular complications were reported in cirrhotic patients in comparison to non-cirrhotic patients who underwent PCI by Alqahtani et al, Lu et al, and Alazzawi et al, and the findings were concordant with our results [ 21 , 22 , 23 ]. Post-PCI gastrointestinal bleeding incidents were found to be higher in the PCI with cirrhosis group in comparison to the control group by Lu et al and Alazzawi et al, corresponding with our study findings [ 21 , 22 ]. Similarly, AKI and post-PCI stroke events were reported to be higher in the cirrhotic group in comparison to the non-cirrhotic group by Alqahtani et al and Lu et al, and the results were concordant with our findings [ 21 , 23 ].…”

“…Of these, 20 were excluded as they either had unmatching target populations, were not primary research articles or case reports, or lacked a comparison arm. Hence, three studies that met the eligibility criteria were included in our study [ 21 , 22 , 23 ]. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram is depicted in Figure S1 .…”

“…The main limitation of our study was that only three studies were included in the final reports. One of the included studies had a very low number of patients and its results had wide confidence intervals; therefore, it was of limited value to the analysis [ 22 ]. Moreover, many of the studies included were observational in nature; therefore, there could be confounders that affected the present results.…”

“… Forest plot of secondary outcomes: ( A ) stroke, ( B ) GI bleeding, ( C ) AKI, and ( D ) vascular complications [ 21 , 22 , 23 ]. …”